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PLD1 anticorps (AA 1-330)

Cet anticorps anti-PLD1 est un anticorps Lapin Polyclonal détectant PLD1 dans WB. Adapté pour Humain et Souris.
N° du produit ABIN3043383

Aperçu rapide pour PLD1 anticorps (AA 1-330) (ABIN3043383)

Antigène

Voir toutes PLD1 Anticorps
PLD1 (Phospholipase D1 (PLD1))

Reactivité

  • 31
  • 9
  • 9
Humain, Souris

Hôte

  • 28
  • 3
Lapin

Clonalité

  • 29
  • 2
Polyclonal

Conjugué

  • 20
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp PLD1 est non-conjugé

Application

  • 15
  • 12
  • 5
  • 5
  • 3
  • 1
Western Blotting (WB)
  • Épitope

    • 11
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-330

    Fonction

    Anti-Phospholipase D1/PLD1 Antibody

    Réactivité croisée (Details)

    No cross-reactivity with other proteins.

    Attributs du produit

    Anti-Phospholipase D1/PLD1 Antibody (ABIN3043383). Tested in WB applications. This antibody reacts with Human, Mouse. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    Purification

    Immunogen affinity purified.

    Immunogène

    E.coli-derived human PLD1 recombinant protein (Position: M1-H330). Human PLD1 shares 91.8% and 90.9% amino acid (aa) sequence identity with mouse and rat PLD1, respectively.

    Isotype

    IgG
  • Indications d'application

    Western blot, 0.1-0.5 μg/mL, Human, Mouse

    Commentaires

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Antigène

    PLD1 (Phospholipase D1 (PLD1))

    Autre désignation

    PLD1

    Sujet

    Synonyms: Phospholipase D1,PLD 1,hPLD1,3.1.4.4,Choline phosphatase 1,Phosphatidylcholine-hydrolyzing phospholipase D1,PLD1,

    Tissue Specificity: Expressed abundantly in the pancreas and heart and at high levels in brain, placenta, spleen, uterus and small intestine. .

    Background: By somatic cell hybrid analysis, PLD1 is mapped to 3q26.31. This gene encodes a phosphatidylcholine-specific phospholipase which catalyzes the hydrolysis of phosphatidylcholine in order to yield phosphatidic acid and choline. The enzyme may play a role in signal transduction and subcellular trafficking. Alternative splicing results in multiple transcript variants with both catalytic and regulatory properties. And PLD1 disrupted association of gamma-secretase protein components, independent of PLD1catalytic activity. What's more, PLD1 regulates intracellular trafficking of beta-amyloid, distinct from its effect on gamma-secretase activity.

    Sequence Similarities: Belongs to the phospholipase D family.

    Poids moléculaire

    124 kDa

    ID gène

    5337

    UniProt

    Q13393
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