SHBG anticorps (AA 30-210)

N° du produit ABIN3043434

Détail du produit anti-SHBG anticorps

Antigène: SHBG (Sex Hormone Binding Globulin (SHBG))

Épitope: AA 30-210

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SHBG est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Sex hormone-binding globulin(SHBG) detection. Tested with WB in Human.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Sex hormone-binding globulin(SHBG) detection. Tested with WB in Human.
Gene Name: sex hormone-binding globulin
Protein Name: Sex hormone-binding globulin

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SHBG recombinant protein (Position: L30-A210). Human SHBG shares 72% amino acid (aa) sequence identity with both mouse and rat SHBG.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for SHBG is approximately 0.1 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur SHBG

Antigène: SHBG (Sex Hormone Binding Globulin (SHBG))

Autre désignation: SHBG (SHBG Produits)

Synonymes: anticorps ABP, anticorps SBP, anticorps TEBG, anticorps Abpa, anticorps shbgl, anticorps wu:fb66h07, anticorps wu:fd55b08, anticorps zgc:123063, anticorps shbg, anticorps sex hormone binding globulin, anticorps sex hormone-binding globulin, anticorps sex hormone binding globulin L homeolog, anticorps SHBG, anticorps Shbg, anticorps shbg, anticorps shbg.L

Sujet: Sex hormone-binding globulin (SHBG) is a glycoprotein that binds to the sex hormones,androgen and estrogen. SHBG is produced mostly by the liver and is released into the bloodstream. Other sites that produce SHBG include the brain, uterus, testes, and placenta. SHBG has both enhancing and inhibiting hormonal influences. It decreases with high levels of insulin, growth hormone, insulin-like growth factor 1 (IGF-1), androgens, prolactin and transcortin. High estrogen, andthyroxine cause it to increase. It has been found that the monosaccharides glucose and fructose reduced human SHBG production by hepatocytes, irrespective of the presence of insulin, by downregulation of hepatocyte nuclear factor-4A and replacement of HNF4A by COUP-TFI at a cis-element within the human SHBG promoter, coincident with repression of its transcriptional activity.

Synonyms: ABP antibody|Androgen binding protein antibody|SBP antibody|Sex hormone-binding globulin antibody|Sex steroid binding protein antibody|Sex steroid-binding protein antibody|SHBG antibody|SHBG_HUMAN antibody|TeBG antibody|Testis specific androgen binding protein antibody|Testis-specific androgen-binding protein antibody|Testosterone binding beta globulin antibody|Testosterone estradiol binding globulin antibody|Testosterone estrogen binding globulin antibody|Testosterone-estradiol-binding globulin antibody|Testosterone-estrogen-binding globulin antibody

ID gène: 6462

UniProt: P04278

Pathways: Hormone Transport