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CCL7 anticorps (AA 24-97)

Cet anticorps anti-CCL7 Polyclonal Lapin (ABIN3043479) détecte spécifiquement CCL7 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Souris.
N° du produit ABIN3043479
500,50 €
Plus frais de livraison 40,00 € et TVA
100 μg
Destination: France
Envoi sous 8 à 11 jours ouvrables

Aperçu rapide pour CCL7 anticorps (AA 24-97) (ABIN3043479)

Antigène

Voir toutes CCL7 Anticorps
CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))

Reactivité

  • 68
  • 14
  • 7
  • 1
  • 1
  • 1
Souris

Hôte

  • 41
  • 32
  • 12
  • 1
Lapin

Clonalité

  • 55
  • 31
Polyclonal

Conjugué

  • 42
  • 14
  • 7
  • 7
  • 6
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp CCL7 est non-conjugé

Application

  • 57
  • 46
  • 19
  • 13
  • 10
  • 8
  • 6
  • 4
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA
  • Épitope

    • 8
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 24-97

    Fonction

    Anti-MCP3/CCL7 Antibody

    Réactivité croisée (Details)

    No cross-reactivity with other proteins

    Attributs du produit

    Anti-MCP3/CCL7 Antibody (ABIN3043479). Tested in ELISA, WB applications. This antibody reacts with Mouse. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    Purification

    Immunogen affinity purified.

    Immunogène

    E.coli-derived mouse MCP3 recombinant protein (Position: Q24-P97). Mouse MCP3 shares 60% and 95% amino acid (aa) sequences identity with human and rat MCP3, respectively.

    Isotype

    IgG
  • Indications d'application

    Western blot, 0.1-0.5 μg/mL, Mouse, -
    ELISA, 0.1-0.5 μg/mL, -

    Commentaires

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Antigène

    CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))

    Autre désignation

    CCL7

    Sujet

    Synonyms: C-C motif chemokine 7,Intercrine/chemokine MARC,Monocyte chemoattractant protein 3,Monocyte chemotactic protein 3,MCP-3,Protein FIC,Small-inducible cytokine A7,Ccl7,Fic, Mcp3, Scya7,

    Tissue Specificity: Found as a hybrid receptor with INSR in muscle, heart, kidney, adipose tissue, skeletal muscle, hepatoma, fibroblasts, spleen and placenta (at protein level). Expressed in a variety of tissues. Overexpressed in tumors, including melanomas, cancers of the colon, pancreas prostate and kidney. .

    Background: Chemokine (C-C motif) ligand 7 (CCL7) is a small cytokine known as a chemokine that was previously called monocyte-specific chemokine 3 (MCP3). It belongs to the C-C chemokine family. By fluorescence in situ hybridization, MCP3 gene is mapped to chromosome 17q11.2-q12. MCP3 was identified as a physiologic substrate of gelatinase A. Cleaved MCP3 binds to CC-chemokine receptors-1, -2, and -3, but no longer induces calcium fluxes or promotes chemotaxis, and instead acts as a general chemokine antagonist that dampens inflammation, it has been found that matrix metalloproteinases are both effectors and regulators of the inflammatory response.

    Sequence Similarities: Belongs to the intercrine beta (chemokine CC) family.

    Poids moléculaire

    36 kDa

    ID gène

    20306

    UniProt

    Q03366
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