BAG2 anticorps (AA 1-211)

N° du produit ABIN3043508

Détail du produit anti-BAG2 anticorps

Antigène: BAG2 (BCL2-Associated Athanogene 2 (BAG2))

Épitope: AA 1-211

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BAG2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for BAG family molecular chaperone regulator 2(BAG2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for BAG family molecular chaperone regulator 2(BAG2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: BCL2-associated athanogene 2
Protein Name: BAG family molecular chaperone regulator 2

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human BAG2 recombinant protein (Position: M1-N211). Human BAG2 shares 93.4% amino acid (aa) sequence identity with mouse BAG2.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur BAG2

Antigène: BAG2 (BCL2-Associated Athanogene 2 (BAG2))

Autre désignation: BAG2 (BAG2 Produits)

Synonymes: anticorps bag2, anticorps MGC89300, anticorps BAG2, anticorps ATBAG2, anticorps BCL-2-associated athanogene 2, anticorps MTG10.13, anticorps MTG10_13, anticorps BAG-2, anticorps dJ417I1.2, anticorps zgc:64195, anticorps 2610042A13Rik, anticorps BC016230, anticorps BCL2 associated athanogene 2, anticorps BCL-2-associated athanogene 2, anticorps BCL2-associated athanogene 2, anticorps Bcl2-associated athanogene 2, anticorps bag2, anticorps BAG2, anticorps Bag2

Sujet: BAG family molecular chaperone regulator 2 is a protein that in humans is encoded by the BAG2 gene. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. The functional antagonisms displayed between BAG family proteins and Hip suggest that a proper balance of these 2 types of protein is required for achieving optimal cycles of substrate binding and release required for inducting conformational changes in proteins, with Hip promoting peptide substrate binding by Hsc70/Hsp70 and BAG family proteins promoting dissociation.

Synonyms: BAG 2 antibody|BAG family molecular chaperone regulator 2 antibody|BAG-2 antibody|BAG-family molecular chaperone regulator-2 antibody|Bag2 antibody|BAG2_HUMAN antibody|BCL 2 associated athanogene 2 antibody|Bcl-2-associated athanogene 2 antibody|BCL2 associated athanogene 2 antibody|BCL2-associated athanogene 2 antibody|dJ417I1.2 (BAG family molecular chaperone regulator 2) antibody|dJ417I1.2 antibody|KIAA0576 antibody|MGC149462 antibody| OTTHUMP00000016668 antibody

ID gène: 9532

UniProt: O95816