Adiponectin Receptor 1 anticorps (N-Term)

N° du produit ABIN3043520

L’anticorps Lapin Polyclonal anti-Adiponectin Receptor 1 a été validé pour WB, ICC et IF. Il convient pour détecter Adiponectin Receptor 1 dans des échantillons de Humain et Rat.

Aperçu rapide pour Adiponectin Receptor 1 anticorps (N-Term) (ABIN3043520)

Antigène: Adiponectin Receptor 1 (ADIPOR1)

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Adiponectin Receptor 1 est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Détail du produit anti-Adiponectin Receptor 1 anticorps

Épitope: AA 51-78, N-Term

Fonction: Anti-Adiponectin Receptor 1/ADIPOR1 Antibody Picoband®

Séquence: EQTCPVPQEE EEEVRVLTLP LQAHHAME

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-Adiponectin Receptor 1/ADIPOR1 Antibody Picoband® (ABIN3043520). Tested in IF, ICC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human ADIPOR1, different from the related mouse sequence by two amino acids.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human, Rat
Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human
1. "Entrez Gene: ADIPOR1 adiponectin receptor 1" 2. Yamauchi T, Kamon J, Ito Y, Tsuchida A, Yokomizo T, Kita S, Sugiyama T, Miyagishi M, Hara K, Tsunoda M, Murakami K, Ohteki T, Uchida S, Takekawa S, Waki H, Tsuno NH, Shibata Y, Terauchi Y, Froguel P, Tobe K, Koyasu S, Taira K, Kitamura T, Shimizu T, Nagai R, Kadowaki T (June 2003). "Cloning of adiponectin receptors that mediate antidiabetic metabolic effects". Nature 423 (6941): 762-9.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur Adiponectin Receptor 1

Antigène: Adiponectin Receptor 1 (ADIPOR1)

Autre désignation: ADIPOR1

Sujet:

Synonyms: Adiponectin receptor protein 1,Progestin and adipoQ receptor family member I,ADIPOR1,PAQR1 , TESBP1A,CGI-45,

Tissue Specificity: Widely expressed (PubMed:16044242). Highly expressed in heart and skeletal muscle (PubMed:12802337). Expressed at intermediate level in brain, spleen, kidney, liver, placenta, lung and peripheral blood leukocytes (PubMed:12802337). Weakly expressed in colon, thymus and small intestine (PubMed:12802337). .

Background: ADIPOR1 is known as Adiponectin receptor protein 1. This gene encodes a protein which acts as a receptor for adiponectin, a hormone secreted by adipocytes which regulates fatty acid catabolism and glucose levels. Binding of adiponectin to the encoded protein results in activation of an AMP-activated kinase signaling pathway which affects levels of fatty acid oxidation and insulin sensitivity. A pseudogene of this gene is located on chromosome 14. Multiple alternatively spliced transcript variants have been found for this gene.

Sequence Similarities: Belongs to the ADIPOR family.

Poids moléculaire: 43 kDa

UniProt: Q96A54

Pathways: AMPK Signaling