PSCA anticorps (AA 21-95)

N° du produit ABIN3043554

Cité dans 2 publications. Cet anticorps anti-PSCA Polyclonal Lapin (ABIN3043554) détecte spécifiquement PSCA dans WB. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PSCA anticorps (AA 21-95) (ABIN3043554)

Antigène: PSCA (Prostate Stem Cell Antigen (PSCA))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSCA est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PSCA anticorps

Épitope: AA 21-95

Fonction: Anti-PSCA Antibody

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: Human PSCA shares 66% amino acid (aa) sequence identity with mouse PSCA.

Attributs du produit: Anti-PSCA Antibody. Tested in WB applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PSCA recombinant protein (Position: L21-S95). Human PSCA shares 66% amino acid (aa) sequence identity with mouse PSCA.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Mouse, Rat, Human

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-PSCA (ABIN3043554)

Wang, Wu, Zhu, Ding, Cai, Ni, Wu, Meng, Zhang, Zhang, Li, Wang, Chen, Jin, Zhang: "PSCA rs2294008 polymorphism contributes to the decreased risk for cervical cancer in a Chinese population." dans: Scientific reports, Vol. 6, pp. 23465, (2017) (PubMed).

Zhao, Ma, Zeng, Qi, Ou, Liang: "Small interference RNA-mediated silencing of prostate stem cell antigen attenuates growth, reduces migration and invasion of human prostate cancer PC-3M cells." dans: Urologic oncology, Vol. 31, Issue 3, pp. 343-51, (2013) (PubMed).

Détails sur PSCA

Antigène: PSCA (Prostate Stem Cell Antigen (PSCA))

Autre désignation: PSCA

Sujet:

Background: PSCA is also known as PRO232. This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. This gene includes a polymorphism that results in an upstream start codon in some individuals, this polymorphism is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants.

Gene Full Name: prostate stem cell antigen

Sequence Similarities: Contains 1 UPAR/Ly6 domain.

Poids moléculaire: 25 kDa

ID gène: 8000

UniProt: O43653