RAB3A anticorps (C-Term)
Aperçu rapide pour RAB3A anticorps (C-Term) (ABIN3043559)
Antigène
Voir toutes RAB3A AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 192-220, C-Term
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Fonction
- Anti-Rab3A Antibody
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Séquence
- DTADPAVTGA KQGPQLSDQQ VPPHQDCAC
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Réactivité croisée (Details)
- No cross-reactivity with other proteins
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Attributs du produit
- Anti-Rab3A Antibody (ABIN3043559). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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Purification
- Immunogen affinity purified.
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Immunogène
- A synthetic peptide corresponding to a sequence at the C-terminus of human Rab3A, different from the related mouse and rat sequences by two amino acids.
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Isotype
- IgG
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Indications d'application
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Western blot, 0.1-0.5 μg/mL, Mouse, Rat, Human
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Commentaires
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- RAB3A (RAB3A, Member RAS Oncogene Family (RAB3A))
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Autre désignation
- RAB3A
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Sujet
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Synonyms: Ras-related protein Rab-3A,RAB3A,
Tissue Specificity: Specifically expressed in brain.
Background: Ras-related protein Rab-3A is a protein that in humans is encoded by the RAB3A gene. This gene is mapped to 19p13.11. Synapsin I stimulated the RAB3A cycle by increasing GTP binding, GTPase activity, and RAB3A recruitment to the synaptic vesicle membrane. Conversely, RAB3A inhibited synapsin I binding to actin and synapsin I-induced synaptic vesicle clustering. It has been found that RAB3A was necessary for both forms of synaptic plasticity, and it is also involved in calcium exocytosis in neurons. In addition to that, RAB3A has been found to regulate a late step in synaptic vesicle fusion.
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Poids moléculaire
- 25 kDa
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ID gène
- 5864
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UniProt
- P20336
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Pathways
- Synaptic Membrane, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
Antigène
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