OTX2 anticorps (C-Term)
Aperçu rapide pour OTX2 anticorps (C-Term) (ABIN3043586)
Antigène
Voir toutes OTX2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 258-289, C-Term
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Fonction
- Anti-Otx2 Antibody
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Séquence
- DYKDQTASWK LNFNADCLDY KDQTSSWKFQ VL
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Réactivité croisée (Details)
- No cross-reactivity with other proteins
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Attributs du produit
- Anti-Otx2 Antibody (ABIN3043586). Tested in WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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Purification
- Immunogen affinity purified.
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Immunogène
- A synthetic peptide corresponding to a sequence at the C-terminus of human Otx2, identical to the related mouse sequence.
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Isotype
- IgG
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Indications d'application
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Western blot, 0.1-0.5 μg/mL, Human
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Commentaires
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- OTX2 (Orthodenticle Homeobox 2 (OTX2))
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Autre désignation
- OTX2
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Sujet
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Synonyms: Homeobox protein OTX2,Orthodenticle homolog 2,OTX2,
Tissue Specificity: Expressed in brain.
Background: OTX2 is also known as CPHD6 or MCOPS5. This gene encodes a member of the bicoid subfamily of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and plays a role in brain, craniofacial, and sensory organ development. The encoded protein also influences the proliferation and differentiation of dopaminergic neuronal progenitor cells during mitosis. Mutations in this gene cause syndromic microphthalmia 5 (MCOPS5) and combined pituitary hormone deficiency 6 (CPHD6). This gene is also suspected of having an oncogenic role in medulloblastoma. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Pseudogenes of this gene are known to exist on chromosomes two and nine.
Sequence Similarities: Belongs to the paired homeobox family. Bicoid subfamily.
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Poids moléculaire
- 32 kDa
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ID gène
- 5015
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UniProt
- P32243
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Pathways
- Dopaminergic Neurogenesis
Antigène
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