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PARK7/DJ1 anticorps (AA 2-189)

PARK7 Reactivité: Humain, Souris, Rat WB, ICC, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3043589
  • Antigène Voir toutes PARK7/DJ1 (PARK7) Anticorps
    PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))
    Épitope
    • 21
    • 16
    • 11
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-189
    Reactivité
    • 93
    • 70
    • 50
    • 8
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 99
    • 15
    • 2
    • 1
    Lapin
    Clonalité
    • 93
    • 24
    Polyclonal
    Conjugué
    • 71
    • 13
    • 9
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PARK7/DJ1 est non-conjugé
    Application
    • 95
    • 44
    • 31
    • 30
    • 26
    • 21
    • 19
    • 15
    • 14
    • 13
    • 5
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Fonction
    Rabbit IgG polyclonal antibody for Protein deglycase DJ-1(PARK7) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
    Réactivité croisée (Details)
    No cross reactivity with other proteins.
    Attributs du produit
    Rabbit IgG polyclonal antibody for Protein deglycase DJ-1(PARK7) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
    Gene Name: parkinson protein 7
    Protein Name: Protein deglycase DJ-1
    Purification
    Immunogen affinity purified.
    Immunogène
    E.coli-derived human PARK7 recombinant protein (Position: A2-D189). Human PARK7 shares 91% amino acid (aa) sequence identity with both mouse and rat PARK7.
    Isotype
    IgG
    Top Product
    Discover our top product PARK7 Anticorps primaire
  • Indications d'application
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for PARK7 is approximately 0.1 ng/lane under reducing conditions.
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Commentaires

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Antigène
    PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))
    Autre désignation
    PARK7 (PARK7 Produits)
    Synonymes
    anticorps DJ-1, anticorps DJ1, anticorps CAP1, anticorps Dj1, anticorps SP22, anticorps dj1, anticorps zgc:103725, anticorps park7b, anticorps park7, anticorps park7a, anticorps Parkinsonism associated deglycase, anticorps Parkinson disease (autosomal recessive, early onset) 7, anticorps parkinson protein 7, anticorps parkinson protein 7 S homeolog, anticorps parkinson protein 7 L homeolog, anticorps PARK7, anticorps Park7, anticorps park7, anticorps park7.S, anticorps park7.L
    Sujet
    Parkinson disease (autosomal recessive, early onset) 7, also known as DJ1, is a protein which in humans is encoded by the PARK7 gene. PARK7 belongs to the peptidase C56 family of proteins. PARK7 is mapped to chromosome 1p36. It acts as a positive regulator of androgen receptor-dependent transcription. It is also involved in tumorigenesis and in maintaining mitochondrial homeostasis. This gene may also function as a redox-sensitive chaperone, as a sensor foroxidative stress, and it apparently protects neurons against oxidative stress and cell death. It has been found that PARK7 mutations that impair transcriptional coactivator function can render dopaminergic neurons vulnerable to apoptosis and may contribute to the pathogenesis of Parkinson disease.

    Synonyms: CAP1 antibody|DJ 1 antibody|DJ-1 antibody|DJ1 antibody|DJ1 protein antibody|FLJ27376 antibody|FLJ34360 antibody|FLJ92274 antibody|Oncogene DJ1 antibody|OTTHUMP00000001348 antibody|OTTHUMP00000001349 antibody|OTTHUMP00000001350 antibody|OTTHUMP00000001351 antibody|Park 7 antibody|Park7 antibody|PARK7_HUMAN antibody|Parkinson disease (autosomal recessive early onset) 7 antibody|Parkinson disease (autosomal recessive, early onset) 7 antibody|Parkinson disease protein 7 antibody|Parkinson protein 7 antibody|Protein DJ 1 antibody|Protein DJ-1 antibody|RNA binding protein regulatory subunit antibody|RS antibody|SP22 antibody
    ID gène
    11315
    UniProt
    Q99497
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Proton Transport
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