TFPI2 anticorps (Middle Region)
Aperçu rapide pour TFPI2 anticorps (Middle Region) (ABIN3043614)
Antigène
Voir toutes TFPI2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Fonction
- Anti-TFPI2 Antibody
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Séquence
- NVTRYYFNPR YRTCDAF
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Specificité
- No cross reactivity with other proteins.
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Réactivité croisée (Details)
- No cross-reactivity with other proteins
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Attributs du produit
- Anti-TFPI2 Antibody. Tested in IHC, WB applications. This antibody reacts with Human.
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Purification
- Immunogen affinity purified.
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Immunogène
- A synthetic peptide corresponding to a sequence in the middle region of human TFPI2.
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Isotype
- IgG
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Indications d'application
- Western blot, 0.1-0.5 μg/mL, Human Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
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Commentaires
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
Date de péremption
- 12 months
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- TFPI2 (Tissue Factor Pathway Inhibitor 2 (TFPI2))
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Autre désignation
- TFPI2
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Sujet
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Background: Tissue factor pathway inhibitor 2, also known as TFPI2, is a human gene which is located at 7q22. It is an important regulator of the extrinsic pathway of blood coagulation through its ability to inhibit factor Xa and factor VIIa-tissue factor activity. After a 22-residue signal peptide, the mature TFPI2 protein contains 213 amino acids with 18 cysteines and 2 canonical N-linked glycosylation sites. The purified recombinant TFPI2 strongly inhibited the amidolytic activities of trypsin and the factor VIIa-tissue factor complex. The latter inhibition was markedly enhanced in the presence of heparin. Mouse TFPI2 mRNA is highly expressed in developing mouse placenta, as in human. And there are also high transcript levels in adult mouse liver and kidney.
Gene Full Name: tissue factor pathway inhibitor 2
Sequence Similarities: Belongs to the nuclear hormone receptor family. NR1 subfamily.
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Poids moléculaire
- 51 kDa
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ID gène
- 7980
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UniProt
- P48307
Antigène
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