XAF1 anticorps (C-Term)
Aperçu rapide pour XAF1 anticorps (C-Term) (ABIN3043705)
Antigène
Voir toutes XAF1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- C-Term
-
Fonction
- Anti-XIAP-associated factor 1 XAF1 Antibody
-
Séquence
- QEKCRWLASS KGKQVRNFS
-
Specificité
- No cross reactivity with other proteins.
-
Réactivité croisée (Details)
- No cross-reactivity with other proteins
-
Attributs du produit
- Anti-XIAP-associated factor 1 XAF1 Antibody. Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human.
-
Purification
- Immunogen affinity purified.
-
Immunogène
- A synthetic peptide corresponding to a sequence at the C-terminus of human XAF1.
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Western blot, 0.1-0.5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry(Fixed), 1-3 μg/1x106 cells, Human
-
Commentaires
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
-
Restrictions
- For Research Use only
-
-
-
Format
- Lyophilized
-
Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
Concentration
- 500 μg/mL
-
Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
-
Conseil sur la manipulation
- Avoid repeated freezing and thawing.
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
Date de péremption
- 12 months
-
-
- XAF1 (XiAP Associated Factor 1 (XAF1))
-
Autre désignation
- XAF1
-
Sujet
-
Background: XIAP associated factor-1, also known as XAF1, is a human gene. X-linked inhibitor of apoptosis (XIAP, MIM 300079) is a potent member of the IAP family. All members of this family possess baculoviral IAP (BIR) repeats, cysteine-rich domains of approximately 80 amino acids that bind and inhibit caspases. XAF1 antagonizes the anticaspase activity of XIAP and may be important in mediating apoptosis resistance in cancer cells. And alteration in XAF1 and XIAP RNA expression levels may lead to increased apoptotic resistance and proliferation due to unregulated XIAP function in cancer cells.
Gene Full Name: XIAP associated factor 1
Sequence Similarities: Contains 1 TRAF-type zinc finger.
-
Poids moléculaire
- 35 kDa
-
ID gène
- 54739
-
UniProt
- Q6GPH4
Antigène
-