p63 anticorps (AA 311-680)

N° du produit ABIN3043716

Détail du produit anti-p63 anticorps

Antigène: p63 (TP63) (Tumor Protein P63 (TP63))

Épitope: AA 311-680

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp p63 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Fonction: Rabbit IgG polyclonal antibody for Tumor protein 63(TP63) detection. Tested with WB, IHC-P, ICC in Human.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Tumor protein 63(TP63) detection. Tested with WB, IHC-P, ICC in Human.
Gene Name: tumor protein p63
Protein Name: Tumor protein 63

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human p63 recombinant protein (Position: S311-E680). Human p63 shares 98% amino acid (aa) sequence identity with both mouse and rat p63.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for p63 is approximately 0.25 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur p63

Antigène: p63 (TP63) (Tumor Protein P63 (TP63))

Autre désignation: TP63 (TP63 Produits)

Synonymes: anticorps AIS, anticorps B(p51A), anticorps B(p51B), anticorps EEC3, anticorps KET, anticorps LMS, anticorps NBP, anticorps OFC8, anticorps RHS, anticorps SHFM4, anticorps TP53CP, anticorps TP53L, anticorps TP73L, anticorps p40, anticorps p51, anticorps p53CP, anticorps p63, anticorps p73H, anticorps p73L, anticorps TP63, anticorps tp63, anticorps DNp63, anticorps id:ibd3516, anticorps tp73l, anticorps wu:fc89f04, anticorps wu:fk85h07, anticorps wu:fk88b02, anticorps Ket, anticorps P73l, anticorps Tp73l, anticorps Trp63, anticorps TRP63, anticorps AI462811, anticorps P51/P63, anticorps P63, anticorps Tp63, anticorps Trp53rp1, anticorps Xp63, anticorps ket, anticorps np63, anticorps tp73l-A, anticorps trp63, anticorps tumor protein p63, anticorps transformation related protein 63, anticorps tumor protein p63 L homeolog, anticorps TP63, anticorps tp63, anticorps Tp63, anticorps Trp63, anticorps tp63.L

Sujet: Tumor protein p63 (TP63), also known as the p63 or TP73L is a protein that in humans is encoded by the TP63 gene. It is mapped to 3q28. TP63 is a member of the p53 family of transcription factors. This gene encodes for two main isoforms by alternative promoters (TAp63 and ΔNp63). TP63 has been mostly restricted to its apoptotic function and more recently as the guardian of oocyte integrity. It has been found that the combined loss of TP63 and p73 results in the failure of cells containing functional p53 to undergo apoptosis in response to DNA damage. TP63 is an essential regulator of stem cell maintenance in stratified epithelial tissues. Tp63 is also critical for maintaining the progenitor-cell populations that are necessary to sustain epithelial development and morphogenesis.

Synonyms: AIS antibody|Amplified in squamous cell carcinoma antibody|B(p51A) antibody|B(p51B) antibody|Chronic ulcerative stomatitis protein antibody|CUSP antibody|DN p63 alpha 1 antibody|DNp63 antibody|EEC3 antibody|Keratinocyte transcription factor antibody|Keratinocyte transcription factor KET antibody|KET antibody|LMS antibody|MGC115972 antibody|MGC192897 antibody|NBP antibody|OFC8 antibody|OTTHUMP00000209732 antibody|OTTHUMP00000209733 antibody|OTTHUMP00000209734 antibody|OTTHUMP00000209735 antibody|OTTHUMP00000209737 antibody|OTTHUMP00000209738 antibody|OTTHUMP00000209739 antibody|OTTHUMP00000209740 antibody|OTTHUMP00000209741 antibody|OTTHUMP00000209742 antibody|OTTHUMP00000209743 antibody|OTTHUMP00000209744 antibody|p40 antibody|p51 antibody|P51/P63 antibody|p53 like transcription factor antibody|p53 related protein antibody|p53-related protein p63 antibody|p53CP antibody|p63 antibody|P63_HUMAN antibody|P73 antibody|p73H antibody|p73L antibody|RHS antibody|SHFM4 antibody|TAp63alpha antibody|TP53CP antibody|TP53L antibody|TP63 antibody|TP73 antibody|TP73L antibody|Transformation related protein 63 antibody|Transformation-related protein 63 antibody|Trp53rp1 antibody|Trp63 antibody|Tumor protein 63 antibody|tumor protein 63 kDa with strong homology to p53 antibody|Tumor protein p53-competing protein antibody|Tumor protein p53-like antibody|tumor protein p63 antibody|Tumor protein p63 deltaN isoform delta antibody|Tumor protein p73 antibody|tumor protein p73-like antibody

ID gène: 8626

UniProt: Q9H3D4