CADM1 anticorps (AA 45-340)

N° du produit ABIN3043770

Cet anticorps anti-CADM1 est un anticorps Polyclonal produit chez le Lapin, détectant CADM1 dans WB et FACS. Convient pour Humain, Souris et Rat.

Aperçu rapide pour CADM1 anticorps (AA 45-340) (ABIN3043770)

Antigène: CADM1 (Cell Adhesion Molecule 1 (CADM1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CADM1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Détail du produit anti-CADM1 anticorps

Épitope: AA 45-340

Fonction: Anti-SynCAM/CADM1 Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-SynCAM/CADM1 Antibody (ABIN3043770). Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SynCAM recombinant protein (Position: Q45-P340). Human SynCAM shares 99% amino acid (aa) sequence identity with mouse SynCAM.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur CADM1

Antigène: CADM1 (Cell Adhesion Molecule 1 (CADM1))

Autre désignation: CADM1

Sujet:

Synonyms: Cell adhesion molecule 1,Immunoglobulin superfamily member 4,IgSF4,Nectin-like protein 2,NECL-2,Spermatogenic immunoglobulin superfamily,SgIgSF,Synaptic cell adhesion molecule,SynCAM,Tumor suppressor in lung cancer 1,TSLC-1,CADM1 ,IGSF4 , IGSF4A, NECL2 , SYNCAM , TSLC1 ,

Tissue Specificity: Expressed in metastatic melanoma, liver, skin, kidney, heart, lung, lymph node, skeletal muscle and brain, and also in A2058 melanoma cells and activated T-cells (at protein level). Expressed in blood vessels. Strongly expressed in endothelial cells, cytotrophoblasts, and poorly differentiated. colon adenocarcinoma cells found in lymphatics. .

Background: Cell adhesion molecule 1 is a protein that, in humans, is encoded by the CADM1 gene. This gene is also known as IGSF4, SYNCAM or TSLC1, and it is mapped to 11q23.3. CADM1 functions as a homophilic cell adhesion molecule at the synapse. Expression of the isolated cytoplasmic tail of CADM1 in neurons inhibited synapse assembly. Conversely, expression of full-length CADM1 in nonneuronal cells induced synapse formation by cocultured hippocampal neurons with normal release properties.

Sequence Similarities: Belongs to the nectin family.

Poids moléculaire: 49 kDa

ID gène: 23705

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Activated T Cell Proliferation