CEBPB anticorps (AA 1-200)

N° du produit ABIN3043809

Cet anticorps anti-CEBPB Polyclonal Lapin (ABIN3043809) détecte spécifiquement CEBPB dans WB, IHC, IF, FACS et ICC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CEBPB anticorps (AA 1-200) (ABIN3043809)

Antigène: CEBPB (CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CEBPB est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Détail du produit anti-CEBPB anticorps

Épitope: AA 1-200

Fonction: Anti-CEBP Beta/CEBPB Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-CEBP Beta/CEBPB Antibody (ABIN3043809). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human CEBP Beta recombinant protein (Position: M1-A200). Human CEBP Beta shares 61% amino acid (aa) sequence identity with both mouse and rat CEBP Beta.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry(Fixed), 1-3 μg/1x10⁶ cells, Human

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and IHC(F).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur CEBPB

Antigène: CEBPB (CCAAT/enhancer Binding Protein (C/EBP), beta (CEBPB))

Autre désignation: CEBPB

Sujet:

Synonyms: CCAAT/enhancer-binding protein beta ,C/EBP beta ,Liver activator protein,LAP,Liver-enriched inhibitory protein,LIP,Nuclear factor NF-IL6,Transcription factor 5,TCF-5,CEBPB ,TCF5,PP9092,

Tissue Specificity: Expressed at low levels in the lung, kidney and spleen.

Background: CCAAT/enhancer-binding protein beta, also known as is CEBP-beta, is a protein that in humans is encoded by the CEBPB gene. It mapped to 20q13.13. The protein encoded by this intronless gene is a bZIP transcription factor that can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma. The encoded protein is important in the regulation of genes involved in immune and inflammatory responses and has been shown to bind to the IL-1 response element in the IL-6 gene, as well as to regulatory regions of several acute-phase and cytokine genes. In addition, the encoded protein can bind the promoter and upstream element and stimulate the expression of the collagen type I gene. CEBP-beta is critical for normal macrophage functioning, an important immune cell sub-type. Observational work has shown that expression of CEBP-beta in blood leukocytes is positively associated with muscle strength in humans, emphasizing the importance of the immune system, and particularly macrophages, in the maintenance of muscle function.

Sequence Similarities: Belongs to the bZIP family. C/EBP subfamily.

Poids moléculaire: 46 kDa

ID gène: 1051

UniProt: P17676

Pathways: Interferon-gamma Pathway, Autophagy, Brown Fat Cell Differentiation