HDAC11 anticorps (N-Term)

N° du produit ABIN3043840

Détail du produit anti-HDAC11 anticorps

Antigène: HDAC11 (Histone Deacetylase 11 (HDAC11))

Épitope: AA 47-81, N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HDAC11 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Histone deacetylase 11(HDAC11) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Séquence: NFLKEEKLLS DSMLVEAREA SEEDLLVVHT RRYLN

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Histone deacetylase 11(HDAC11) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: histone deacetylase 11
Protein Name: Histone deacetylase 11

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human HDAC11 (47-81aa NFLKEEKLLSDSMLVEAREASEEDLLVVHTRRYLN), different from the related mouse sequence by one amino acid.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur HDAC11

Antigène: HDAC11 (Histone Deacetylase 11 (HDAC11))

Autre désignation: HDAC11 (HDAC11 Produits)

Synonymes: anticorps CG31119, anticorps DHDACX, anticorps Dmel\\CG31119, anticorps HDAC11, anticorps HDACX, anticorps dHDAC11, anticorps dmHDA403, anticorps zgc:91942, anticorps HD11, anticorps histone deacetylase 11, anticorps Histone deacetylase 11, anticorps hypothetical protein, anticorps HDAC11, anticorps hdac11, anticorps CpipJ_CPIJ001619, anticorps Bm1_15905, anticorps LOAG_18214, anticorps Hdac11

Sujet: Histone deacetylase 11 is a 39 kDa histone deacetylase enzyme that in humans is encoded by the HDAC11 gene on chromosome 3 in humans and chromosome 6 in mice. This gene encodes a class IV histone deacetylase. And the encoded protein is localized to the nucleus and may be involved in regulating the expression of interleukin 10. Alternative splicing results in multiple transcript variants. HDAC11 expression is normally found in brain and testis tissue, but upregulation of HDAC11 expression has also been seen in various cancer cells. In addition, HDAC11 has been shown to be a negative regulator of IL-10 production in antigen presenting cells. It has also been shown that inhibition of HDAC11 results in increased expression of OX40L in Hodgkin lymphoma cells.

Synonyms: FLJ22237 antibody|HD 11 antibody|HD11 antibody|HDA11_HUMAN antibody|HDAC 11 antibody|HDAC11 antibody|Histone deacetylase 11 antibody

ID gène: 79885