SFTPA2 anticorps (C-Term)

N° du produit ABIN3043922

L’anticorps Lapin Polyclonal anti-SFTPA2 a été validé pour WB, IHC, IF et IHC (fro). Il convient pour détecter SFTPA2 dans des échantillons de Humain, Rat et Souris.

Aperçu rapide pour SFTPA2 anticorps (C-Term) (ABIN3043922)

Antigène: SFTPA2 (Surfactant Associated Protein A2 (SFTPA2))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SFTPA2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-SFTPA2 anticorps

Épitope: AA 206-237, C-Term

Fonction: Anti-SFTPA1/2 Antibody Picoband®

Séquence: VNYTNWYRGE PAGRGKEQCV EMYTDGQWND RN

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-SFTPA1/2 Antibody Picoband® (ABIN3043922). Tested in IF, IHC, IHC-F, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human SFTPA1/2, different from the related mouse sequence by four amino acids, and from the related rat sequence by five amino acids.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Mouse, Rat, -
Immunofluorescence, 5 μg/mL, Rat
1. Perez-Gil J, Weaver TE (June 2010). "Pulmonary surfactant pathophysiology: current models and open questions".Physiology (Bethesda) 25 (3): 132-41. 2. Phelps DS (2001). "Surfactant regulation of host defense function in the lung: a question of balance". Pediatr Pathol Mol Med 20 (4): 269-92.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur SFTPA2

Antigène: SFTPA2 (Surfactant Associated Protein A2 (SFTPA2))

Autre désignation: SFTPA2

Sujet:

Synonyms: Pulmonary surfactant-associated protein A2,PSP-A,PSPA,SP-A,SP-A2,35 kDa pulmonary surfactant-associated protein,Alveolar proteinosis protein,Collectin-5,SFTPA2,COLEC5, PSAP, SFTP1, SFTPA, SFTPA2B,

Tissue Specificity: Expressed in B-cell lines and T-lymphocytes. .

Background: SFTPA1/2 is also known as SP-A. SFTPA1 encodes a lung surfactant protein that is a member of a subfamily of C-type lectins called collectins. The encoded protein binds specific carbohydrate moieties found on lipids and on the surface of microorganisms. This protein plays an essential role in surfactant homeostasis and in the defense against respiratory pathogens. Mutations in this gene are associated with idiopathic pulmonary fibrosis. Alternate splicing results in multiple transcript variants. SFTPA2 is one of several genes encoding pulmonary-surfactant associated proteins (SFTPA) located on chromosome 10. Mutations in this gene and a highly similar gene located nearby, which affect the highly conserved carbohydrate recognition domain, are associated with idiopathic pulmonary fibrosis. The current version of the assembly displays only a single centromeric SFTPA gene pair rather than the two gene pairs shown in the previous assembly which were thought to have resulted from a duplication.

Sequence Similarities: Belongs to the SFTPA family.

Poids moléculaire: 26 kDa

ID gène: 653509, 729238