NRF1 anticorps (Middle Region)

N° du produit ABIN3044020

Cet anticorps Lapin Polyclonal détecte spécifiquement NRF1 dans WB, IHC et ICC. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.Il a été cité dans 1 publication.

Aperçu rapide pour NRF1 anticorps (Middle Region) (ABIN3044020)

Antigène: NRF1 (Nuclear Respiratory Factor 1 (NRF1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NRF1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Détail du produit anti-NRF1 anticorps

Épitope: Middle Region

Fonction: Anti-Nuclear respiratory factor 1 NRF1 Antibody

Séquence: QHGREDLLYA FEDQQTQ

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: identical to the related rat,mouse sequences.

Attributs du produit: Anti-Nuclear respiratory factor 1 NRF1 Antibody. Tested in IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human NRF1, identical to the related rat and mouse sequences.

Isotype: IgG

Information d'application

Indications d'application: Immunocytochemistry , 0.5-1 μg/mL, Human, Mouse, RatImmunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat, MouseWestern blot, 0.1-0.5 μg/mL, Human, Rat, Mouse

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-NRF1 (ABIN3044020)

Sun, Zhong, Zhang, Zhou: "Defect of mitochondrial respiratory chain is a mechanism of ROS overproduction in a rat model of alcoholic liver disease: role of zinc deficiency." dans: American journal of physiology. Gastrointestinal and liver physiology, Vol. 310, Issue 3, pp. G205-14, (2016) (PubMed).

Détails sur NRF1

Antigène: NRF1 (Nuclear Respiratory Factor 1 (NRF1))

Autre désignation: NRF1

Sujet:

Background: Nuclear respiratory factor 1, is also known as NRF1. This gene encodes a protein that homodimerizes and functions as a transcription factor which activates the expression of some key metabolic genes regulating cellular growth and nuclear genes required for respiration, heme biosynthesis, and mitochondrial DNA transcription and replication. The protein has also been associated with the regulation of neurite outgrowth. Alternative splicing results in multiple transcript variants. Confusion has occurred in bibliographic databases due to the shared symbol of NRF1 for this gene and for nuclear factor (erythroid-derived 2)-like 1 which has an official symbol of NFE2L1.

Gene Full Name: nuclear respiratory factor 1

Sequence Similarities: Belongs to the NRF1/Ewg family.

Poids moléculaire: 75 kDa

ID gène: 4899

UniProt: Q16656

Pathways: Regulation of Lipid Metabolism by PPARalpha