KLF3 anticorps (N-Term)

N° du produit ABIN3044105

L’anticorps Lapin Polyclonal anti-KLF3 a été validé pour WB. Il convient pour détecter KLF3 dans des échantillons de Humain, Souris et Rat.

Aperçu rapide pour KLF3 anticorps (N-Term) (ABIN3044105)

Antigène: KLF3 (Kruppel-Like Factor 3 (Basic) (KLF3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KLF3 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-KLF3 anticorps

Épitope: AA 20-34, N-Term

Fonction: Anti-Krueppel-like factor 3 KLF3 Antibody Picoband®

Séquence: SYPSNYMESM KPNKY

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-Krueppel-like factor 3 KLF3 Antibody (ABIN3044105). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human KLF3, different from the related rat sequence by one amino acid, and from the related mouse sequence by two amino acids.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
1. Suske, G., Bruford, E., Philipsen, S.Mammalian SP/KLF transcription factors: bring in the family.Genomics 85: 551-556, 2005. 2. Turner, Jeremy, Nicholas Hannah, Bishop David, Matthews Jacqueline M, Crossley Merlin "The LIM protein FHL3 binds basic Krüppel-like factor/Krüppel-like factor 3 and its co-repressor C-terminal-binding protein 2". J. Biol. Chem. (United States) 278 (15): 12786-95. 2003 3. Wang MJ, Qu XH, Wang LS, et al.. "[cDNA cloning, subcellular localization and tissue expression of a new human Krüppel-like transcription factor: human basic Krüppel-like factor (hBKLF)]". Yi Chuan Xue Bao 30 (1): 1-9. 2003.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur KLF3

Antigène: KLF3 (Kruppel-Like Factor 3 (Basic) (KLF3))

Autre désignation: KLF3

Sujet:

Synonyms: Krueppel-like factor 3;Basic krueppel-like factor;CACCC-box-binding protein BKLF;TEF-2;KLF3;BKLF;

Background: KLF3 (Krueppel-like factor 3) is a protein that in humans is encoded by the KLF3 gene. It is also known as BKLF (Basic kruppel-like factor). KLF3 is a member of the Krüppel-like factors family of transcription factors. KLF3 primarily represses transcription through the transcriptional corepressor C-terminal binding protein (CtBP). Suske et al. (2005) stated that the human KLF3 gene maps to chromosome 4p14, and the mouse Klf3 gene maps to chromosome 5C3.3. Suske et al. (2005) stated that the human and mouse KLF3 proteins contain 345 and 344 amino acids, respectively. Both have a characteristic zinc finger domain, but lack the N-terminal buttonhead box found in related SP transcription factors. The repression mediated through KLF3 is also partially dependent on the sumoylation of its K10 and K197. Within KLF3's C-terminal, which is highly conserved throughout the KLF family, resides three C2H2 zinc fingers that preferentially bind the site NRG GNG NGR.

Sequence Similarities: Belongs to the krueppel C2H2-type zinc-finger protein family.

Poids moléculaire: 18 kDa

UniProt: P57682