SOD3 anticorps (N-Term)

N° du produit ABIN3044113

Détail du produit anti-SOD3 anticorps

Antigène: SOD3 (Superoxide Dismutase 3, Extracellular (SOD3))

Épitope: AA 41-56, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SOD3 est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Fonction: Rabbit IgG polyclonal antibody for Extracellular superoxide dismutase[Cu-Zn](SOD3) detection. Tested with WB, IHC-P, IHC-F, ICC in Human.

Séquence: KVTEIWQEVM QRRDDD

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Extracellular superoxide dismutase[Cu-Zn](SOD3) detection. Tested with WB, IHC-P, IHC-F, ICC in Human.
Gene Name: superoxide dismutase 3, extracellular
Protein Name: Extracellular superoxide dismutase[Cu-Zn]

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human SOD3 (41-56aa KVTEIWQEVMQRRDDD).

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human
IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Human
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P), IHC(F) and ICC.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Références pour anticorps anti-SOD3 (ABIN3044113)

Li, Xiao, Li, Li, Zeng, Liu, Liang, Li, Chu, Yang: "Hydrogen sulfide reduced renal tissue fibrosis by regulating autophagy in diabetic rats." dans: Molecular medicine reports, Vol. 16, Issue 2, pp. 1715-1722, (2018) (PubMed).

Wu, Ming, Zhang, Wu, Wu, Yao: "Edaravone rescues the lung by inhibiting lipid peroxidation and pro-inflammatory cytokines in a rat model." dans: Chinese medical journal, Vol. 127, Issue 5, pp. 968-70, (2014) (PubMed).

Détails sur SOD3

Antigène: SOD3 (Superoxide Dismutase 3, Extracellular (SOD3))

Autre désignation: SOD3 (SOD3 Produits)

Synonymes: anticorps EC-SOD, anticorps ECSOD, anticorps SOD3, anticorps AI314465, anticorps LOC780439, anticorps fb05f10, anticorps si:dkey-117m1.6, anticorps sod3, anticorps wu:fb05f10, anticorps ECSODPT, anticorps CuZnSOD, anticorps SODA.4, anticorps superoxide dismutase 3, anticorps superoxide dismutase 3, extracellular, anticorps superoxide dismutase 3, extracellular b, anticorps superoxide dismutase 1, anticorps superoxide dismutase precursor ,putative, anticorps SOD3, anticorps Sod3, anticorps sod3b, anticorps sod3, anticorps Sod1, anticorps Smp_095980

Sujet: SOD3(SUPEROXIDE DISMUTASE 3) also called SUPEROXIDE DISMUTASE, EXTRACELLULAR, EC-SOD, and Cu-Zn, is an enzyme that in humans is encoded by the SOD3 gene. This gene encodes a member of the superoxide dismutase(SOD) protein family. SODs are antioxidant enzymes that catalyze the dismutation of two superoxide radicals into hydrogen peroxide and oxygen. Hendrickson et al.(1990) mapped the SOD3 gene to 4pter-q21 by a study of somatic cell hybrids. Stern et al.(2003) narrowed the assignment to 4p15.3-p15.1 by somatic cell and radiation hybrid analysis, linkage mapping, and FISH. The product of this gene is though to protect the brain, lungs, and other tissues from oxidative stress. The protein is secreted into the extracellular space and forms a glycosylated homotetramer that is anchored to the extracellular matrix(ECM) and cell surfaces through an interaction with heparan sulfate proteoglycan and collagen. A fraction of the protein is cleaved near the C-terminus before secretion to generate circulating tetramers that do not interact with the ECM.

Synonyms: EC SOD antibody|EC-SOD antibody|Extracellular superoxide dismutase[Cu Zn] antibody|Extracellular superoxide dismutase[Cu-Zn] antibody|Extracellular superoxide dismutase antibody|Extracellular superoxide dismutase precursor antibody|MGC20077 antibody|SOD 3 antibody|SOD3 antibody|SODE_HUMAN antibody|Superoxide dismutase 3 extracellular antibody

UniProt: P08294