TFF1 anticorps (Middle Region)

N° du produit ABIN3044263

Détail du produit anti-TFF1 anticorps

Antigène: TFF1 (Trefoil Factor 1 (TFF1))

Épitope: AA 67-84, Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TFF1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Trefoil factor 1(TFF1) detection. Tested with WB, IHC-P in Human.

Séquence: WCFYPNTIDV PPEEECEF

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Trefoil factor 1(TFF1) detection. Tested with WB, IHC-P in Human.
Gene Name: trefoil factor 1
Protein Name: Trefoil factor 1

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human Estrogen Inducible Protein pS2(67-84aa WCFYPNTIDVPPEEECEF).

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur TFF1

Antigène: TFF1 (Trefoil Factor 1 (TFF1))

Autre désignation: TFF1 (TFF1 Produits)

Synonymes: anticorps BCEI, anticorps D21S21, anticorps HP1.A, anticorps HPS2, anticorps pNR-2, anticorps pS2, anticorps Bcei, anticorps PS2, anticorps bcei, anticorps d21s21, anticorps hp1.a, anticorps hps2, anticorps p1, anticorps p1-a, anticorps pnr-2, anticorps ps2, anticorps tff1, anticorps xP1, anticorps xp1-L, anticorps xp1, anticorps TFF1, anticorps Ps2, anticorps trefoil factor 1, anticorps trefoil factor 1 S homeolog, anticorps trefoil factor 1, gene 2 S homeolog, anticorps TFF1, anticorps Tff1, anticorps tff1.S, anticorps tff1.2.S, anticorps LOC100358238

Sujet: TFF1(Trefoil factor 1), also known as pS2, is a protein that in humans is encoded by the TFF1 gene. Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. It is found that TFF1 in normal human urine inhibited the growth of calcium oxalate crystals. Urinary TFF1 showed an inhibitory potency similar to that of nephrocalcin, and inhibition was dose dependent and inhibited by TFF1 antisera, particularly by antisera directed to the TFF1 C terminus. Concentrations and relative amounts of TFF1 in the urine of patients with idiopathic calcium oxalate kidney stones were significantly less than those found in controls. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.

Synonyms: BCEI antibody|Breast cancer estrogen inducible protein antibody|Breast cancer estrogen inducible sequence antibody|Breast cancer estrogen-inducible protein antibody|D21S21 antibody|Gastrointestinal trefoil protein antibody|Gastrointestinal trefoil protein pS2 antibody|hP1.A antibody|HP1A antibody|HPS 2 antibody|HPS2 antibody|pNR 2 antibody|PNR-2 antibody|pNR2 antibody|Polypeptide P1.A antibody|Protein pS2 antibody|PS 2 antibody|pS2 antibody|pS2 protein antibody|TFF 1 antibody|TFF1 antibody|TFF1_HUMAN antibody|Trefoil factor 1 antibody

UniProt: P04155

Pathways: EGFR Signaling Pathway