Tenascin R anticorps (N-Term)

N° du produit ABIN3044266

Cet anticorps Lapin Polyclonal détecte spécifiquement Tenascin R dans IHC et WB. Il présente une réactivité envers Humain, Rat et Souris.

Aperçu rapide pour Tenascin R anticorps (N-Term) (ABIN3044266)

Antigène: Tenascin R (TNR) (Tenascin R (Restrictin, Janusin) (TNR))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Tenascin R est non-conjugé

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Détail du produit anti-Tenascin R anticorps

Épitope: AA 104-117, N-Term

Fonction: Anti-Tenascin-R TNR Antibody Picoband®

Séquence: QTSDHESQVT FTHK

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-Tenascin-R TNR Antibody (ABIN3044266). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of mouse TNR, identical to the related rat sequence, and different from the related human sequence by one amino acid.

Isotype: IgG

Information d'application

Indications d'application: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Rat, Human, Mouse
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. Leprini, A., Gherzi, R., Siri, A., Querze, G., Viti, F., Zardi, L.The human tenascin-R gene.J. Biol. Chem. 271: 31251-31254, 1996. 2. Saghatelyan, A., de Chevigny, A., Schachner, M., Lledo, P.-M.Tenascin-R mediates activity-dependent recruitment of neuroblasts in the adult mouse forebrain.Nature Neurosci. 7: 347-356, 2004. 3. Williams, H., Schachner, M., Wang, B., Kenwrick, S.Radiation hybrid mapping of the genes for tenascin-R (TNR), phosducin (PDC), Laminin C1 (LAMC1), and TAX in 1q25-q32.Genomics 46: 165-166, 1997.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Tenascin R

Antigène: Tenascin R (TNR) (Tenascin R (Restrictin, Janusin) (TNR))

Autre désignation: TNR

Sujet:

Synonyms: Tenascin-R,TN-R,Janusin,Restrictin,TNR,

Tissue Specificity: Brain specific. .

Background: Tenascin-R is a protein that in humans is encoded by the TNR gene. Tenascin-R (TNR) is an extracellular matrix protein expressed primarily in the central nervous system. It is a member of the tenascin (TN) gene family, which includes at least 3 genes in mammals: TNC (or hexabrachion), TNX (TNXB), and TNR. The genes are expressed in distinct tissues at different times during embryonic development and are present in adult tissues. TNR has been detected predominantly in the central nervous system and is localized around motor neurons and on motor axons in the spinal cord, cerebellum, hippocampus, and olfactory bulb. It is suggested that tenascin-R has a role in initiating the detachment of neuroblasts from tangential chains and in initiating radial migration of the cells.

Sequence Similarities: Belongs to the tenascin family.

Poids moléculaire: 150 kDa

UniProt: Q92752

Pathways: Regulation of Cell Size