MMP24 anticorps (N-Term)

N° du produit ABIN3044304

Détail du produit anti-MMP24 anticorps

Antigène: MMP24 (Matrix Metallopeptidase 24 (Membrane-inserted) (MMP24))

Épitope: AA 208-225, N-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MMP24 est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Matrix metalloproteinase-24(MMP24) detection. Tested with WB in Human,Mouse,Rat.

Séquence: YHEIKSDRKE ADIMIFFA

Réactivité croisée (Details): Predicted Cross Reactivity: mouse, rat
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Attributs du produit: Rabbit IgG polyclonal antibody for Matrix metalloproteinase-24(MMP24) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: matrix metallopeptidase 24(membrane-inserted)
Protein Name: Matrix metalloproteinase-24

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human MMP24(208-225aa YHEIKSDRKEADIMIFFA), identical to the related mouse and rat sequences.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Références pour anticorps anti-MMP24 (ABIN3044304)

Liu, Liu, Tan, Tang, Long, Li, Liang, Chu, Yang: "Gaseous signalling molecule SO2 via Hippo‑MST pathway to improve myocardial fibrosis of diabetic rats." dans: Molecular medicine reports, Vol. 16, Issue 6, pp. 8953-8963, (2018) (PubMed).

Li, Li, Zeng, Liu, Yang: "H2S improves renal fibrosis in STZ-induced diabetic rats by ameliorating TGF-β1 expression." dans: Renal failure, Vol. 39, Issue 1, pp. 265-272, (2017) (PubMed).

Détails sur MMP24

Antigène: MMP24 (Matrix Metallopeptidase 24 (Membrane-inserted) (MMP24))

Autre désignation: MMP24 (MMP24 Produits)

Synonymes: anticorps MMP-24, anticorps MMP25, anticorps MT-MMP 5, anticorps MT-MMP5, anticorps MT5-MMP, anticorps MT5MMP, anticorps MTMMP5, anticorps AU040325, anticorps Mt5-mmp, anticorps si:ch211-239j9.5, anticorps MMP24, anticorps mt3-mmp, anticorps matrix metallopeptidase 24, anticorps matrix metallopeptidase 16 S homeolog, anticorps MMP24, anticorps Mmp24, anticorps mmp24, anticorps mmp16.S

Sujet: Matrix metalloproteinase-24, also known as MT5MMP or MMP25, is an enzyme that in humans is encoded by the MMP24 gene. Proteins of the matrix metalloproteinase(MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP(MT-MMP) subfamily, each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 by cleavage. The gene has previously been referred to as MMP25 but has been renamed MMP24. This gene may be a proteoglycanase involved in degradation of proteoglycans, such as dermatan sulfate and chondroitin sulfate proteoglycans.

Synonyms: Matrix metallopeptidase 24(membrane inserted) antibody|Matrix metallopeptidase 24 antibody|Membrane type 5 matrix metalloproteinase antibody|Membrane type matrix metalloproteinase 5 antibody|Membrane-type matrix metalloproteinase 5 antibody|Membrane-type-5 matrix metalloproteinase antibody|MMP 24 antibody|MMP 25 antibody|MMP-24 antibody|Mmp24 antibody|MMP24_HUMAN antibody|MMP25 antibody|MT MMP5 antibody|MT-MMP 5 antibody|MT5 MMP antibody|MT5-MMP antibody|MT5MMP antibody|MTMMP5 antibody|Processed matrix metalloproteinase-24 antibody

UniProt: Q9Y5R2