Myoglobin anticorps (C-Term)

N° du produit ABIN3044306

L’anticorps Lapin Polyclonal anti-Myoglobin a été validé pour WB et IHC. Il convient pour détecter Myoglobin dans des échantillons de Humain, Rat et Souris. Il y a 2+ publications disponibles.

Aperçu rapide pour Myoglobin anticorps (C-Term) (ABIN3044306)

Antigène: Myoglobin (MB)

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Myoglobin est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-Myoglobin anticorps

Épitope: AA 138-154, C-Term

Fonction: Anti-Myoglobin/MB Antibody Picoband®

Séquence: LFRNDIAAKY KELGFQG

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Rabbit IgG polyclonal antibody for Myoglobin(MB) detection. Tested with WB, IHC-P in Mouse,Rat.
Gene Name: myoglobin
Protein Name: myoglobin

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of mouse Myoglobin, identical to the related rat sequence.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat
1. Boyer, S. H., Fainer, D. C., Naughton, M. A. Myoglobin inherited structural variation in man. Science 140: 1228-1231, 1963. 2. Boulton, F. E., Huntsman, R. G., Lorkin, P. A., Lehmann, H. Abnormal human myoglobin: 53(D4) glutamic acid lysine. Nature 223: 832-833, 1969. 3. Jeffreys, A. J., Wilson, V., Blanchetot, A., Weller, P., Geurts van Kessel, A., Spurr, N., Solomon, E., Goodfellow, P. The human myoglobin gene: a third dispersed globin locus in the human genome. Nucleic Acids Res. 12: 3235-3243, 1984.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-Myoglobin (ABIN3044306)

Xu, He, Zhang, Fan, Zhao, Xu, Nie, Li, Huang, Lu, Xu: "Synthesis and in vitro evaluation of a hyaluronic acid-quantum dots-melphalan conjugate." dans: Carbohydrate polymers, Vol. 121, pp. 132-9, (2015) (PubMed).

Peng, Yanjiao, Ai-guo, Pengtao, Jianhua, Ju, Hongsheng, Xichen: "A fine balance between CCNL1 and TIMP1 contributes to the development of breast cancer cells." dans: Biochemical and biophysical research communications, Vol. 409, Issue 2, pp. 344-9, (2011) (PubMed).

Détails sur Myoglobin

Antigène: Myoglobin (MB)

Autre désignation: Myoglobin

Sujet:

Synonyms: Myoglobin,Mb,

Background: Myoglobin (MB) also known as PVALB, is a single-chain globular protein of 153 or 154 amino acids, containing a heme (iron-containing porphyrin) prosthetic group in the center around which the remaining apoprotein folds. It is a member of the globin superfamily and is expressed in skeletal and cardiac muscles. This gene is mapped to chromosome 22q11-q13. Myoglobin is released from damaged muscle tissue (rhabdomyolysis), which has very high concentrations of myoglobin. The released myoglobin is filtered by the kidneys but is toxic to the renal tubular epithelium and so may cause acute renal failure.

Poids moléculaire: 17 kDa

UniProt: P04247

Pathways: Brown Fat Cell Differentiation