MORG1 anticorps (N-Term)

N° du produit ABIN3044326

Détail du produit anti-MORG1 anticorps

Antigène: MORG1 (wdr83) (WD Repeat Domain 83 (wdr83))

Épitope: AA 29-43, N-Term

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MORG1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for WD repeat domain-containing protein 83(WDR83) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Séquence: RAVRFNVDGN YCLTC

Réactivité croisée (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Attributs du produit: Rabbit IgG polyclonal antibody for WD repeat domain-containing protein 83(WDR83) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: WD repeat domain 83
Protein Name: WD repeat domain-containing protein 83

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human Morg1(29-43aa RAVRFNVDGNYCLTC), identical to the related mouse and rat sequences.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur MORG1

Antigène: MORG1 (wdr83) (WD Repeat Domain 83 (wdr83))

Autre désignation: WDR83 (wdr83 Produits)

Synonymes: anticorps MORG1, anticorps 1500041N16Rik, anticorps Morg1, anticorps RGD1306947, anticorps morg1, anticorps MAPK organizer 1, anticorps wu:fj29g04, anticorps zgc:92654, anticorps WD repeat domain 83, anticorps WD repeat domain containing 83, anticorps WD repeat domain 83 L homeolog, anticorps WDR83, anticorps Wdr83, anticorps wdr83.L, anticorps wdr83

Sujet: MORG1(mitogen-activated protein kinase organizer 1), a member of the WD-40 protein family that was isolated as a binding partner of the extracellular signal-regulated kinase(ERK) pathway scaffold protein MP1. MORG1 specifically associates with several components of the ERK pathway, including MP1, Raf-1, MEK, and ERK, and stabilizes their assembly into an oligomeric complex. MORG1 facilitates ERK activation when cells are stimulated with lysophosphatidic acid, phorbol 12-myristate 13-acetate, or serum, but not in response to epidermal growth factor. Suppression of MORG1 by short interfering RNA leads to a marked reduction in ERK activity when cells are stimulated with serum. MORG1 is a component of a modular scaffold system that participates in the regulation of agonist-specific ERK signaling.

Synonyms: MAPK organizer 1 antibody|MGC4238 antibody|Mitogen activated protein kinase organizer 1 antibody|Mitogen-activated protein kinase organizer 1 antibody|MORG 1 antibody|WD repeat domain-containing protein 83 antibody|wdr83 antibody|WDR83_HUMAN antibody