IFITM1 anticorps (N-Term)

N° du produit ABIN3044336

Il existe 3+ publications pour ce produit. L’anticorps anti-IFITM1 Polyclonal Lapin est utilisé pour la détection de IFITM1 dans des échantillons de Humain. Il a été validé pour WB et IHC.

Aperçu rapide pour IFITM1 anticorps (N-Term) (ABIN3044336)

Antigène: IFITM1 (Interferon-Induced Transmembrane Protein 1 (IFITM1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IFITM1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-IFITM1 anticorps

Épitope: N-Term

Fonction: Anti-IFITM1 Antibody

Séquence: MHKEEHEVAV LGPPPST

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-IFITM1 Antibody. Tested in IHC, WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human IFITM1.

Isotype: IgG

Information d'application

Indications d'application: Immunohistochemistry (Frozen Section), 0.5-1 μg/mL, Human, -Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, HumanWestern blot, 0.1-0.5 μg/mL, Human

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and IHC(F).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-IFITM1 (ABIN3044336)

Ma, Zhang, Fu, Xia, Zhan, Li, Wang, Wu: "Wnt signaling may be activated in a subset of Peutz-Jeghers syndrome polyps closely correlating to LKB1 expression." dans: Oncology reports, Vol. 23, Issue 6, pp. 1569-76, (2010) (PubMed).

Xu, Yang, Hu: "Binding of IFITM1 enhances the inhibiting effect of caveolin-1 on ERK activation." dans: Acta biochimica et biophysica Sinica, Vol. 41, Issue 6, pp. 488-94, (2009) (PubMed).

Yang, Xu, Chen, Hu: "IFITM1 plays an essential role in the antiproliferative action of interferon-gamma." dans: Oncogene, Vol. 26, Issue 4, pp. 594-603, (2007) (PubMed).

Détails sur IFITM1

Antigène: IFITM1 (Interferon-Induced Transmembrane Protein 1 (IFITM1))

Autre désignation: IFITM1

Sujet:

Background: Interferon-induced Transmembrane Protein 1 (IFITM1), also called Interferon-induced Protein 17 (IFI17). IFITM1 activity is required for primordial germ cells (PGCs) transit from the mesoderm into the endoderm, and that it appears to act via a repulsive mechanism, such that PGCs avoid Ifitm1-expressing tissues. It is mapped to Chr.11 and belongs to the family of interferon-induced transmembrane proteins (Ifitm/mil/fragilis), which encodes cell surface proteins that may modulate cell adhesion and influence cell differentiation. Interferon-inducible membrane proteins of approximately 17 kDa have been suggested to play a role in the antiproliferative activity of interferons based on their pattern of induction in interferon-sensitive and -resistant cell lines and the ability of a membrane fraction enriched in 17- kDa proteins to inhibit cell growth.

Gene Full Name: interferon induced transmembrane protein 1

Sequence Similarities: Belongs to the intermediate filament family.

Poids moléculaire: 70-74 kDa

ID gène: 8519

UniProt: P13164