Muscarinic Acetylcholine Receptor M2 anticorps (C-Term)

N° du produit ABIN3044369

Détail du produit anti-Muscarinic Acetylcholine Receptor M2 anticorps

Antigène: Muscarinic Acetylcholine Receptor M2 (CHRM2) (Cholinergic Receptor, Muscarinic 2 (CHRM2))

Épitope: AA 356-370, C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Muscarinic Acetylcholine Receptor M2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Muscarinic acetylcholine receptor M2(CHRM2) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Séquence: EKQNIVARKI VKMTK

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Muscarinic acetylcholine receptor M2(CHRM2) detection. Tested with WB, IHC-P in Human, Mouse, Rat.
Gene Name: cholinergic receptor, muscarinic 2
Protein Name: Muscarinic acetylcholine receptor M2

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human Muscarinic Acetylcholine Receptor 2(356-370aa EKQNIVARKIVKMTK), identical to the related rat and mouse sequences.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat, The detection limit for CHRM2 is approximately 1 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Muscarinic Acetylcholine Receptor M2

Antigène: Muscarinic Acetylcholine Receptor M2 (CHRM2) (Cholinergic Receptor, Muscarinic 2 (CHRM2))

Autre désignation: CHRM2 (CHRM2 Produits)

Synonymes: anticorps HM2, anticorps AChR-M2, anticorps Chrm-2, anticorps M2, anticorps chrm2, anticorps Acm2, anticorps GPM2, anticorps cholinergic receptor muscarinic 2, anticorps cholinergic receptor, muscarinic 2, cardiac, anticorps cholinergic receptor, muscarinic 2a, anticorps cholinergic receptor, muscarinic 2, anticorps CHRM2, anticorps Chrm2, anticorps chrm2a

Sujet: The muscarinic acetylcholine receptor M2, also known as the cholinergic receptor, muscarinic 2, is a muscarinic acetylcholine receptor that in humans is encoded by the CHRM2 gene. The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene.

Synonyms: 7TM receptor antibody|Acetylcholine receptor, muscarinic, 2 antibody|Acm2 antibody|ACM2_HUMAN antibody|Cholinergic receptor muscarinic 2 antibody|Cholinergic receptor, muscarinic 2, cardiac antibody|Cholinergic receptor, muscarinic 2, isoform a antibody|Cholinergic receptor, muscarinic 2a antibody|CHRM 2 antibody|CHRM2 antibody|chrm2a antibody|CM2 antibody|FLJ43243 antibody|HM 2 antibody|HM2 antibody|M2 antibody|M2 muscarinic receptor antibody|MGC120006 antibody|MGC120007 antibody|Muscarinic acetylcholine receptor M2 antibody|Muscarinic M2 receptor antibody

UniProt: P08172