GABRA1 anticorps (C-Term)

N° du produit ABIN3044445

Cité dans 1 publication. Cet anticorps anti-GABRA1 Polyclonal Lapin (ABIN3044445) détecte spécifiquement GABRA1 dans WB et IHC. L’anticorps est réactif avec des échantillons de Rat, Humain et Souris.

Aperçu rapide pour GABRA1 anticorps (C-Term) (ABIN3044445)

Antigène: GABRA1 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1))

Reactivité: Rat, Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GABRA1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-GABRA1 anticorps

Épitope: C-Term

Fonction: Anti-GABA A Receptor alpha 1/GABRA1 Antibody

Séquence: ATYLNREPQL KAPTPHQ

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: identical to the related rat,mouse sequences.

Attributs du produit: Anti-GABA A Receptor alpha 1/GABRA1 Antibody. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human GABA A Receptor alpha 1, identical to the related rat and mouse sequences.

Isotype: IgG

Information d'application

Indications d'application: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Rat, Human, MouseWestern blot, 0.1-0.5 μg/mL, Human, Rat, Mouse

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-GABRA1 (ABIN3044445)

Bao, Wang, Wei, Wang, Wuyun, Bo: "Role of microRNA-4458 in patients with non-small-cell lung cancer." dans: Oncology letters, Vol. 12, Issue 5, pp. 3958-3966, (2016) (PubMed).

Détails sur GABRA1

Antigène: GABRA1 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1))

Autre désignation: GABRA1

Sujet:

Background: GABRA1, Gamma-aminobutyric acid receptor subunit alpha-1, is a protein that in humans is encoded by the GABRA1 gene. The 1,055-bp GABRA1 clone contained an open reading frame and 260 nucleotides in the 5-prime noncoding region. The 351-amino acid sequence shows 97 % homology with its bovine counterpart. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.

Gene Full Name: gamma-aminobutyric acid type A receptor subunit alpha1

Sequence Similarities: Belongs to the ligand-gated ion channel (TC 1.A.9) family. Gamma-aminobutyric acid receptor (TC 1.A.9.5) subfamily. GABRA1 sub-subfamily.

Poids moléculaire: 52 kDa

ID gène: 2554

UniProt: P14867