CXCL5 anticorps (AA 38-130)

N° du produit ABIN3044514

Cet anticorps anti-CXCL5 est un anticorps Lapin Polyclonal détectant CXCL5 dans WB et ELISA. Adapté pour Rat.

Aperçu rapide pour CXCL5 anticorps (AA 38-130) (ABIN3044514)

Antigène: CXCL5 (Chemokine (C-X-C Motif) Ligand 5 (CXCL5))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CXCL5 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-CXCL5 anticorps

Épitope: AA 38-130

Fonction: Anti-CXCL5 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-CXCL5 Antibody Picoband® (ABIN3044514). Tested in ELISA, WB applications. This antibody reacts with Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived rat CXCL5 recombinant protein (Position: A38-Q130). Rat CXCL5 shares 58.7% and 76.3% amino acid (aa) sequence identity with human and mouse CXCL5, respectively.

Isotype: IgG

Information d'application

Indications d'application: ELISA, 0.1-0.5 μg/mL, -
Western blot, 0.1-0.5 μg/mL, Rat
1. "Entrez Gene: CXCL5 chemokine (C-X-C motif) ligand 5". 2. Chang MS, McNinch J, Basu R, Simonet S (Nov 1994). "Cloning and characterization of the human neutrophil-activating peptide (ENA-78) gene". J Biol Chem 269 (41): 25277-82. 3. Persson T, Monsef N, Andersson P, Bjartell A, Malm J, Calafat J, Egesten A (2003). "Expression of the neutrophil-activating CXC chemokine ENA-78/CXCL5 by human eosinophils". Clin. Exp. Allergy 33 (4): 531-7.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur CXCL5

Antigène: CXCL5 (Chemokine (C-X-C Motif) Ligand 5 (CXCL5))

Autre désignation: Cxcl5

Sujet:

Synonyms: C-X-C motif chemokine 5,Cytokine LIX,Small-inducible cytokine B5,Cxcl5,Scyb5,

Tissue Specificity: At least expressed in the lung and trachea.

Background: C-X-C motif chemokine 5?or ENA-78 is a?protein?that in humans is encoded by the?CXCL5?gene. The protein encoded by this gene, CXCL5 is a small?cytokine?belonging to the CXC?chemokine?family. It is produced following stimulation of cells with the inflammatory cytokines?interleukin-1?or?tumor necrosis factor-alpha.?Expression of CXCL5 has also been observed ineosinophils, and can be inhibited with the type II?interferon?IFN-γ. This chemokine stimulates the chemotaxis of neutrophils possessing?angiogenic?properties. It elicits these effects by interacting with the cell surface?chemokine receptor?CXCR2.?The?gene?for CXCL5 is encoded on four?exons?and is located on human?chromosome 4?amongst several other CXC chemokine genes.?CXCL5 has been implicated in connective tissue remodelling.?Also, CXCL5 has been described to regulate neutrophil homeostasis.

Poids moléculaire: 14 kDa

ID gène: 105988538

UniProt: P97885

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity