Fatty Acid Synthase anticorps (AA 1-226)

N° du produit ABIN3044520

Détail du produit anti-Fatty Acid Synthase anticorps

Antigène: Fatty Acid Synthase (FASN)

Épitope: AA 1-226

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Fatty Acid Synthase est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Fatty acid synthase(FASN) detection. Tested with WB, IHC-P in Human.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Fatty acid synthase(FASN) detection. Tested with WB, IHC-P in Human.
Gene Name: fatty acid synthase
Protein Name: Fatty acid synthase

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human FASN recombinant protein (Position: M1-E226). Human FASN shares 90.3% and 90.7% amino acid (aa) sequence identity with mouse and rat FASN, respectively.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Références pour anticorps anti-Fatty Acid Synthase (ABIN3044520)

Lu, Ma, Cai: "Increased HAGLR expression promotes non-small cell lung cancer proliferation and invasion via enhanced de novo lipogenesis." dans: Tumour biology, Vol. 39, Issue 4, pp. 1010428317697570, (2017) (PubMed).

Détails sur Fatty Acid Synthase

Antigène: Fatty Acid Synthase (FASN)

Autre désignation: FASN (FASN Produits)

Synonymes: anticorps FAS, anticorps OA-519, anticorps SDR27X1, anticorps FASN, anticorps fj34h12, anticorps wu:fj34h12, anticorps Cgl0836, anticorps A630082H08Rik, anticorps BcDNA:GH07626, anticorps BcDNA:gh07626, anticorps DM_7295848, anticorps Dmel\\CG3523, anticorps Fatty acid synthase, anticorps anon-EST:Posey235, anticorps anon-EST:Posey43, anticorps anon-WO0138581.1, anticorps dFAS, anticorps fas, anticorps fatty acid synthase, anticorps fatty acid synthase Fas, anticorps type I polyketide synthase, anticorps Fatty acid synthase Fas, anticorps Fatty Acid SyNthase, anticorps fatty-acid synthase, anticorps fatty-acid synthase II, anticorps fatty-acid synthase fas, anticorps Fatty acid synthase 1, anticorps FASN, anticorps fas, anticorps Fasn, anticorps BAD_RS01360, anticorps fasn, anticorps fasn-1, anticorps NCgl0802, anticorps fasB, anticorps MT2600, anticorps TBMG_01448, anticorps FASN1

Sujet: Fatty acid synthase (FAS) is an enzyme that in humans is encoded by the FASN gene. It is mapped to 17q25. The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha.

Synonyms: [Acyl-carrier-protein] S acetyltransferase antibody|[Acyl-carrier-protein] S malonyltransferase antibody|3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase antibody|3-oxoacyl-[acyl-carrier-protein] reductase antibody|3-oxoacyl-[acyl-carrier-protein] synthase antibody|Enoyl-[acyl-carrier-protein] reductase antibody|FAS antibody|FAS_HUMAN antibody|FASN antibody|Fatty acid synthase antibody| MGC14367 antibody|MGC15706 antibody|OA 519 antibody|Oleoyl-[acyl-carrier-protein] hydrolase antibody|SDR27X1 antibody|Short chain dehydrogenase/reductase family 27X member 1 antibody

ID gène: 2194

UniProt: P49327

Pathways: AMPK Signaling