CXCL7 anticorps (AA 55-128)

N° du produit ABIN3044533

Cet anticorps Lapin Polyclonal détecte spécifiquement CXCL7 dans WB, IHC et ELISA. Il présente une réactivité envers Humain.

Aperçu rapide pour CXCL7 anticorps (AA 55-128) (ABIN3044533)

Antigène: CXCL7 (PPBP) (Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) (PPBP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CXCL7 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-CXCL7 anticorps

Épitope: AA 55-128

Fonction: Anti-NAP2/PPBP Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-NAP2/PPBP Antibody Picoband® (ABIN3044533). Tested in ELISA(Cap), IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived humn NAP2 recombinant protein (Position: S55-D128).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human, -
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
ELISA(Cap) , 1-5 μg/mL, Human, -
1. "Entrez Gene: PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)". 2. Hristov M, Zernecke A, Bidzhekov K, et al. (March 2007). "Importance of CXC chemokine receptor 2 in the homing of human peripheral blood endothelial progenitor cells to sites of arterial injury".Circ. Res. 100 (4): 590-7. 3. Majumdar S, Gonder D, Koutsis B, Poncz M (1991). "Characterization of the human beta-thromboglobulin gene. Comparison with the gene for platelet factor 4". J Biol Chem 266 (9): 5785-9.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur CXCL7

Antigène: CXCL7 (PPBP) (Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) (PPBP))

Autre désignation: PPBP

Sujet:

Synonyms: Platelet basic protein;PBP;C-X-C motif chemokine 7;Leukocyte-derived growth factor;LDGF;Macrophage-derived growth factor;MDGF;Small-inducible cytokine B7;Connective tissue-activating peptide III;CTAP-III;LA-PF4;Low-affinity platelet factor IV;TC-2;Connective tissue-activating peptide III (1-81);CTAP-III (1-81);Beta-thromboglobulin;Beta-TG;Neutrophil-activating peptide 2 (74);NAP-2 (74);Neutrophil-activating peptide 2 (73);NAP-2 (73);Neutrophil-activating peptide 2;NAP-2;TC-1;Neutrophil-activating peptide 2 (1-66);NAP-2 (1-66);Neutrophil-activating peptide 2 (1-63);NAP-2 (1-63);PPBP;CTAP3, CXCL7, SCYB7, TGB1, THBGB1;

Tissue Specificity: Restricted to the nervous system. Highly expressed in postmitotic neurons of the developing and postnatal cerebral cortex and hippocampus. .

Background: Chemokine (C-X-C motif) ligand 7  (CXCL7), also known as NAP2 or Pro-Platelet basic protein  (PPBP), is a human gene. The protein encoded by this gene is a platelet-derived growth factor that belongs to the CXC chemokine family. This growth factor is a potent chemoattractant and activator of neutrophils. It has been shown to stimulate various cellular processes including DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by synovial cells. Furthermore, the protein is an antimicrobial protein with bactericidal and antifungal activity.

Poids moléculaire: 19 kDa

ID gène: 5473

UniProt: P02775