RNH1 anticorps (N-Term)

N° du produit ABIN3044540

L’anticorps Lapin Polyclonal anti-RNH1 a été validé pour WB, IHC, FACS et ICC. Il convient pour détecter RNH1 dans des échantillons de Humain, Souris, Rat et Singe.

Aperçu rapide pour RNH1 anticorps (N-Term) (ABIN3044540)

Antigène: RNH1 (Ribonuclease/angiogenin Inhibitor 1 (RNH1))

Reactivité: Humain, Souris, Rat, Singe

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RNH1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Détail du produit anti-RNH1 anticorps

Épitope: AA 2-37, N-Term

Fonction: Anti-Ribonuclease Inhibitor/RNH1 Antibody Picoband®

Séquence: SLDIQSLDIQ CEELSDARWA ELLPLLQQCQ VVRLDD

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-Ribonuclease Inhibitor/RNH1 Antibody Picoband® (ABIN3044540). Tested in Flow Cytometry, IHC, ICC, WB applications. This antibody reacts with Human, Monkey, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human RNH1, different from the related mouse sequence by five amino acids, and from the related rat sequence by four amino acids.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
Immunohistochemistry (Frozen Section), 0.5-1 μg/mL
Immunocytochemistry, 0.5-1 μg/mL
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells
1. "Entrez Gene: RNH1 ribonuclease/angiogenin inhibitor 1". 2. Weremowicz S, Fox EA, Morton CC, Vallee BL (1991). "The placental ribonuclease inhibitor (RNH) gene is located on chromosome subband 11p15.5.". Genomics 8(4): 717-21. 3. Zneimer SM, Crawford D, Schneider NR, Beutler B (1991). "Mapping of the human ribonuclease inhibitor gene (RNH) to chromosome 11p15 by in situ hybridization.". Genomics 8 (1): 175-8.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur RNH1

Antigène: RNH1 (Ribonuclease/angiogenin Inhibitor 1 (RNH1))

Autre désignation: RNH1

Sujet:

Synonyms: Ribonuclease inhibitor,Placental ribonuclease inhibitor,Placental RNase inhibitor,Ribonuclease/angiogenin inhibitor 1,RAI,RNH1,PRI, RNH,

Tissue Specificity: Widely expressed, high expression found in skeletal muscle. .

Background: Ribonuclease inhibitor is an enzyme that in humans is encoded by the RNH1 gene. Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular Rnases. In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin. Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover, the interaction of eukaryotic cells with ribonuclease may be reversible in vivo.

Poids moléculaire: 50 kDa

ID gène: 6050

UniProt: P13489