STIP1 anticorps (C-Term)

N° du produit ABIN3044551

Cet anticorps Lapin Polyclonal détecte spécifiquement STIP1 dans WB. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour STIP1 anticorps (C-Term) (ABIN3044551)

Antigène: STIP1 (Stress-Induced-phosphoprotein 1 (STIP1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp STIP1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-STIP1 anticorps

Épitope: AA 505-543, C-Term

Fonction: Anti-STIP1 Antibody Picoband®

Séquence: RLILEQMQKD PQALSEHLKN PVIAQKIQKL MDVGLIAIR

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-STIP1 Antibody Picoband® (ABIN3044551). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human STIP1, identical to the related mouse and rat sequences.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. Chen, S., Smith, D. F. Hop as an adaptor in the heat shock protein 70 (Hsp70) and Hsp90 chaperone machinery. J. Biol. Chem. 273: 35194-35200, 1998. 2. Song, Y., Masison, D. C. Independent regulation of Hsp70 and Hsp90 chaperones by Hsp70/Hsp90-organizing protein Sti1 (Hop1).J. Biol. Chem. 280: 34178-34185, 2005.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur STIP1

Antigène: STIP1 (Stress-Induced-phosphoprotein 1 (STIP1))

Autre désignation: STIP1

Sujet:

Synonyms: Stress-induced-phosphoprotein 1,STI1,Hsc70/Hsp90-organizing protein,Hop,Renal carcinoma antigen NY-REN-11,Transformation-sensitive protein IEF SSP 3521,STIP1,

Tissue Specificity: Widely expressed. Expressed in brain, pancreas, heart, skeletal muscles, liver, lung, kidney and placenta.

Background: STIP1 is an adaptor protein that coordinates the functions of HSP70 and HSP90 in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones. The International Radiation Hybrid Mapping Consortium mapped the STIP1 gene to 11q13.

Poids moléculaire: 63 kDa

ID gène: 10963

UniProt: P31948