D-Dimer (Fibrin Degradation Product) anticorps
Aperçu rapide pour D-Dimer (Fibrin Degradation Product) anticorps (ABIN305022)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- Specific for human D-dimer and high molecular weight fibrin degradation products, but does not cross-react with fibrinogen (D-monomer). D-dimers are the principle degradation products of cross-linked fibrin, released into the bloodstream following the digestion of fibrin clots (thrombus) by the enzyme plasmin, and thus measurement of the level of D-dimer in plasma, can be used as an indication of thrombotic disorders. Conditions in which levels of D-dimer are elevated include deep vein thrombosis (DVT), venous thromboembolism (VTE), cardiovascular disease and disseminated intravascular coagulation (DIC), a possible acute condition arising from surgical operations, septic shock and liver disease. Can be used as the capture antibody in matched pair ELISA for the detection of D-dimer in human plasma. Plasma samples must be diluted with 10 mM Tris-HCl buffer, pH 7.5, containing 1 M NaCl (final concentration in sample >0.5 M) and 0.1 % Tween 20.
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Purification
- Affinity purified
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Immunogène
- Homogenized fibrin clot.
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Isotype
- IgG2a
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Indications d'application
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Approved: ELISA, WB
Usage: ELISA: This product may be used in an indirect ELISA or as the capture antibody in sandwich ELISA in conjunction with the antibodies clone DD6 (LS-C58116), clone DD4 (LS-C58114) or clone DD5 (LS-C58115), for the detection of D-dimer in human plasma. Plasma samples must be diluted with 10 mM Tris-HCl buffer, pH 7.5, containing 1 M NaCl (final concentration in sample >0.5 M) and 0.1 % Tween 20. -
Commentaires
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, pH 7.4, 0.09 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
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Short term: -20°C
Long term: -20°C.
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- D-Dimer (Fibrin Degradation Product)
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Autre désignation
- Fibrin Degradation Product D-Dimer
Antigène
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