Nanog anticorps (AA 1-154)
Aperçu rapide pour Nanog anticorps (AA 1-154) (ABIN306464)
Antigène
Voir toutes Nanog (NANOG) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- AA 1-154
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Purification
- The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography
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Immunogène
- Recombinant human Nanog (1-154aa) purified from E. coli
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Isotype
- IgG2a kappa
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Indications d'application
- Recommended dilution 1:500
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C,-80 °C
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Stockage commentaire
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- Nanog (NANOG) (Nanog Homeobox (NANOG))
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Autre désignation
- Nanog
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Sujet
- Nanog is a multidomain homeobox transcription factor that functions to maintain the undifferentiated state of pluripotent stem cells. Nanog expression counteracts the differentiation-promoting signals induced by the extrinsic factors LIF, Stat3 and BMP. When Nanog expression is downregulated, cell differentiation can proceed. Proteins that regulate Nanog expression include transcription factors Oct4, SOX2, FoxD3, and Tcf3 and tumor suppressor p53.
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NCBI Accession
- NP_079141
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Pathways
- Stem Cell Maintenance
Antigène
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