MAGI (PDZ 4-5) anticorps

N° du produit ABIN306589

Cet anticorps Mouton Polyclonal détecte spécifiquement MAGI (PDZ 4-5) dans WB. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour MAGI (PDZ 4-5) anticorps (ABIN306589)

Antigène: MAGI (PDZ 4-5) (MAGI) (Membrane AssociatedGuanalyate Kinase (PDZ 4-5) (MAGI))

Reactivité: Humain

Hôte: Mouton

Clonalité: Polyclonal

Application: Western Blotting (WB)

Détail du produit anti-MAGI (PDZ 4-5) anticorps

Fonction: Sheep anti Human Guanalyate Kinase (PDZ 4-5) (MAGI)

Attributs du produit: Membrane-associated guanylate kinase with inverted orientation (MAGI3) is a novel, 130 kDa guanylate kinase which is part of a family of multi-PDZ domain containing guanylate kinases. These guanylate kinases are localized to epithelial cell tight junctions. MAGI3 and PTEN/MMAC cooperate to modulate the kinase activity of AKT/protein kinase B (PKB). MAGI3 positions the PTEN/MMAC phosphatase to specific subcellular locations that are involved with the regulation of cell proliferation and survival. MAGI3, as well as other proteins in this family, are made up of an N-terminal guanylate kinase domain, followed by a WW domain, named for two conserved tryptophan residues and first identified as two repeats in mouse YAP65, which is then followed by 6 PDZ domains.

Purification: Ammonium Sulfate Precipitation

Immunogène: Recombinant protein corresponding to PDZ domains 4-5 of MAGI-3.

Isotype: IgG

Information d'application

Indications d'application: Antibody detects MAGI-3 by Western blot at 1-10 μg/mL. Detects a 130 kDa band in cells transfected with full-length MAGI-3 protein. Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/ml

Buffer: phosphate buffered saline with 0.08 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Détails sur MAGI (PDZ 4-5)

Antigène: MAGI (PDZ 4-5) (MAGI) (Membrane AssociatedGuanalyate Kinase (PDZ 4-5) (MAGI))

Sujet: Sheep anti-Membrane-associated guanylate cyclase of inverted orientation-3, PSD95 DiscsLarge Z01 domains 4-5

UniProt: Q9H2V6