PPP2R5D anticorps

N° du produit ABIN306653

L’anticorps anti-PPP2R5D Polyclonal Lapin est utilisé pour la détection de PPP2R5D dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB.

Aperçu rapide pour PPP2R5D anticorps (ABIN306653)

Antigène: PPP2R5D (Protein Phosphatase 2, Regulatory Subunit B', delta (PPP2R5D))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PPP2R5D est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-PPP2R5D anticorps

Fonction: Rabbit anti Human Protein Phosphatase 2 A/B delta

Réactivité croisée: Boeuf (Vache), Humain, Souris, Rat

Attributs du produit: PP2A is a heterotrimeric phosphatase, ccomposed of A, B and C subunits. The structural A and catalytic C subunits form the constitutive core of the enzyme, which associates with one of a large number of regulatory B subunits. Three families of B subunits have been identified thus far. The prototypical B (or PR55) family of subunits is encoded by three genes, B , B and B . The B' (or B56) family consists of at least seven splice variants derived from five genes. RNA's for the two members of the B'' family, PR72 and PR130, arise by alternative splicing or use of alternate transcription start sites from the same gene. Primary structures as well as functions of B and B' subunits are conserved from yeast to mammals. B is a novel isoform of the B class of PP2A regulatory subunits. It is widely expressed in rat tissues and appears to be involved in targeting PP2A to the cytosolic compartment.

Purification: Ammonium Sulfate Precipitation

Immunogène: Synthetic peptide conjugated to KLH derived from the N-terminus of PP2A/B delta

Isotype: IgG

Information d'application

Indications d'application: Detects PP2A/B delta protein in rat testis by Western blot. Detects a 53 kDa band in rat brain, heart, lung, placenta, skeletal muscle, spleen, testis and thymus tissues lysates. Optimal concentration should be evaluated by serial dilutions. Applications: Western Blotting, Immunofluorescence

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: phosphate buffered saline with 0.08 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Détails sur PPP2R5D

Antigène: PPP2R5D (Protein Phosphatase 2, Regulatory Subunit B', delta (PPP2R5D))

Autre désignation: Protein Phosphatase 2 A/B delta

Sujet: Pp2A/Bd, rabbit anti protein phosphatase 2A, B subunit delta, PP2A B subunit delta

UniProt: Q14738, Q925E7, P56932

Pathways: Signalisation PI3K-Akt, Activation of Innate immune Response, Toll-Like Receptors Cascades