Cet anticorps anti-Phosphotyrosine Monoclonal Souris conjugué à Rhodamine (Clone PY20) (ABIN306708) détecte spécifiquement Phosphotyrosine dans WB, IP, IHC et EIA.
Aperçu rapide pour Phosphotyrosine anticorps (Rhodamine) (ABIN306708)
Antigène
Phosphotyrosine
Hôte
Souris
Clonalité
Monoclonal
Conjugué
Cet anticorp Phosphotyrosine est conjugé à/à la Rhodamine
Application
Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), Enzyme Immunoassay (EIA)
Clone
PY20
Fonction
Mouse anti Phosphotyrosine, conjugated with rhodamine
Attributs du produit
The role of tyrosine phosphorylation in transduction of the mitogenic signal from transmembrane receptors and in transformation by oncogene tyrosine kinases has been the subject of intense investigation for several years. While the phosphorylation of specific tyrosine residues has been shown to be a primary mechanism of signal transduction during normal mitogenesis, cell cycle progression and oncogenic transformation, its role in other areas such as differentiation and gap junction communication, is a matter of active and ongoing research. Antibodies that specifically recognize phosphorylated tyrosine residues have proved to be invaluable to the study of tyrosine -phosphorylated proteins and the biochemical pathways in which they function. The rhodamine conjugate of clone PY20 anti-phosphotyrosine is especially useful for the detection of these P-Tyr proteins in immunohistochemical and immunocytochemical protocols in situations wherein the use of a secondary antibody would complicate detection of the protein(s) of interest.
Purification
Prot A/G
Immunogène
Hybridoma produced from Balb/C mice immunized with phosphotyrosine coupled to carrier protein.