ARHGEF2 anticorps

N° du produit ABIN306728

L’anticorps anti-ARHGEF2 Polyclonal Mouton est utilisé pour la détection de ARHGEF2 dans des échantillons de Souris. Il a été validé pour WB, IF et IP.

Aperçu rapide pour ARHGEF2 anticorps (ABIN306728)

Antigène: ARHGEF2 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 2 (ARHGEF2))

Reactivité: Souris

Hôte: Mouton

Clonalité: Polyclonal

Conjugué: Cet anticorp ARHGEF2 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP)

Détail du produit anti-ARHGEF2 anticorps

Réactivité croisée: Souris

Attributs du produit: Rho guanine nucleotide exchange factor 2, ARHGEF2,Lfc is a 118 kDa protein discovered in a screen for oncogenes in NIH 3T3 cells. Lfc is a signaling protein related to Lbc and is part of the Dbl family of proteins. Lfc is a guanine-nucleotide exchange factor (GEF) for the Rho family of small GTPases. Lfc has also been shown to be upstream of the serine-threonine kinase JNK. Lfc has also been shown to mediate the activation of the Rac signaling pathway.

Purification: Ammonium Sulfate Precipitation

Immunogène: Antibody developed using protein corresponding to amino acids 2 to 447 of the Lfc protein fused to GST.

Isotype: IgG

Information d'application

Indications d'application: Detects Lfc in mouse tissues by immunoprecipitation-Western blot at 4 μg/mL. Detects a 118 kDa band in mouse tissue extracts corresponding to wild-type Lfc. Can also be used in immunofluorescence assays. Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Stockage

Buffer: Provided as solution in phosphate buffered saline with 0.08 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Détails sur ARHGEF2

Antigène: ARHGEF2 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 2 (ARHGEF2))

Autre désignation: LFC

Pathways: Negative Regulation of intrinsic apoptotic Signaling