S1PR5 anticorps

N° du produit ABIN306731

L’anticorps anti-S1PR5 Polyclonal Lapin est utilisé pour la détection de S1PR5 dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour S1PR5 anticorps (ABIN306731)

Antigène: S1PR5 (Sphingosine-1-Phosphate Receptor 5 (S1PR5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp S1PR5 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-S1PR5 anticorps

Fonction: Rabbit anti Human Sphingosine 1 Phosphate Receptor 5 CT (EDG-8)

Réactivité croisée: Humain

Attributs du produit: Endothelial Cell Differentiation Gene-8 (EDG-8) belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG-8 is sphingosine-1-phosphate. There are 8 known members of the EDG receptor family and they are implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG-8 is expressed in oligodendrocytes and fibrous astrocytes in the rat brain.

Purification: Ammonium Sulfate Precipitation

Isotype: IgG

Information d'application

Indications d'application: Detects recombinant EDG8 receptors by Western blot (5-10 μg/mL) at 42 kDa. Due to low expression of EDG receptors, we recommend use of Pierce Femto Signal substrate for western blot development. Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Stockage

Stock: -20 °C

Stockage commentaire: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Détails sur S1PR5

Antigène: S1PR5 (Sphingosine-1-Phosphate Receptor 5 (S1PR5))

Autre désignation: Sphingosine 1 Phosphate Receptor 5 CT (EDG-8)

Sujet: Endothelial Cell Differentiation Gene-8 Receptor C-Terminal

UniProt: Q9H228