SMC2 anticorps (AA 523-768)
Aperçu rapide pour SMC2 anticorps (AA 523-768) (ABIN306862)
Antigène
Voir toutes SMC2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Épitope
- AA 523-768
-
Réactivité croisée
- Humain
-
Attributs du produit
- CAP-E, Structural maintenance of chromosomes protein 2, SMC-2,CAP-E and CAP-C (Chromosome Associated Protein-E & C) are also SMC (Structural Maintenance of Chromosome) family members that form a heterodimeric complex required for mitotic chromosome condensation to achieve proper segregation of genetic information during subsequent cell division. hCAP-C/hCAP-E is a component of a multiprotein complex called condensin that interacts with phosphorylation of Histone H3 resulting in the mitotic chromosome condensation. The distribution patterns of the two heterodimeric complexes in interphase nucleus indicate independent behaviour of the two complexes during cell cycle. These results suggest that the two distinct complexes are involved in different aspects of mitotic chromosome organization in human cells.
-
Purification
- Protein A/G Chromatography
-
Immunogène
- Hybridoma produced by the fusion of splenocytes from mice immunized with recombinant protein corresponding to amino acids 523-768 of human CAP-E and mouse myeloma cells.
-
Isotype
- IgG
-
-
-
-
Indications d'application
- This antibody can be used for Western blotting (1-5 μg/mL). Optimal concentration should be evaluated by serial dilutions.
-
Restrictions
- For Research Use only
-
-
-
Buffer
- Provided as solution in phosphate buffered saline with 0.08 % sodium azide
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- -20 °C
-
Stockage commentaire
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
-
-
- SMC2 (Structural Maintenance of Chromosomes 2 (SMC2))
-
Autre désignation
- Chromosome Associated Protein-E
-
UniProt
- O95347
Antigène
-