APCS anticorps (full length)

N° du produit ABIN306863

L’anticorps anti-APCS Polyclonal Lapin est utilisé pour la détection de APCS dans des échantillons de Humain. Il a été validé pour WB et IP.

Aperçu rapide pour APCS anticorps (full length) (ABIN306863)

Antigène: APCS (Amyloid P Component, Serum (APCS))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APCS est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-APCS anticorps

Épitope: full length

Fonction: Rabbit anti Human SH21A (SH2 DOMAIN-CONTAINING PROTEIN 1A) / (SAP)

Réactivité croisée: Humain

Attributs du produit: SLAM (Signaling Lymphocyte-Activation Molecule) is a glycosylated type-I transmembrane protein which is present on the surface of B and T cells. SLAM is a high-affinity self-ligand which, when triggered, co-activated B or T lymphocyte responses and is considered to be important in bi-directional T - B cell stimulation. SAP (SLAM-Associated Protein) has been determined to be a 15 kDa protein. SAP is believed to the genetic defect which cauases X-linked Lymphoproliferative Syndrome (XLP). SAP is thought to bind to SLAM by the SH2 domain of the SAP protein. Binding of SAP to the SLAM protein blocks the binding of SHP-2 to the phosphorylated SLAM protein which causes XLP.

Purification: Ammonium Sulfate Precipitation

Immunogène: Full-length recombinant SAP protein

Isotype: IgG

Information d'application

Indications d'application: This antibody can be used for Western blotting (5-10 μg/mL) and immunoprecipiation. Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: phosphate buffered saline with 0.08 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Détails sur APCS

Antigène: APCS (Amyloid P Component, Serum (APCS))

Autre désignation: SAP

Sujet: SAP, DSHP, SLAM ASSOCIATED PROTEIN

UniProt: O60880