Sphingosine 1 Phosphate 3 Receptor (EDG-3) anticorps

N° du produit ABIN306917

L’anticorps anti-Sphingosine 1 Phosphate 3 Receptor (EDG-3) Polyclonal Lapin est utilisé pour la détection de Sphingosine 1 Phosphate 3 Receptor (EDG-3) dans des échantillons de Humain et Souris. Il a été validé pour IP et WB.

Aperçu rapide pour Sphingosine 1 Phosphate 3 Receptor (EDG-3) anticorps (ABIN306917)

Antigène: Sphingosine 1 Phosphate 3 Receptor (EDG-3)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Immunoprecipitation (IP), Western Blotting (WB)

Détail du produit

Fonction: x1327k2

Réactivité croisée: Humain, Souris

Attributs du produit: Endothelial cell differentation gene-3 (EDG3) belongs to a family of G-protein couple receptors whose ligands are lysophospholipids. The ligand for EDG3 is sphingosine-1-phosphate. There are 8 known members of the EDG receptor family. They have been implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. The couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG3 is expressed in cardiovascular, leukocyte-containing and other tissues.

Purification: Ammonium Sulfate Precipitation

Information d'application

Indications d'application: Antibody can be used for Western blotting (5-10 μg/mL) and Immunoprecipitation (see reference 4). Optimal concentration should be evaluated by serial dilutions. Due to low expression of EDG receptors, we recommend use of Pierce Femto Signal substrate for western blot development.

Restrictions: For Research Use only

Stockage

Stock: -20 °C

Stockage commentaire: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Détail du antigène

Antigène: Sphingosine 1 Phosphate 3 Receptor (EDG-3)

Sujet: Endothelial cell differentiation gene 3 C-terminal, Sphingosine-1-Phosphate Receptor-3 (S1P3)

UniProt: Q99500