RGR anticorps (Intracellular)
Aperçu rapide pour RGR anticorps (Intracellular) (ABIN306933)
Antigène
Voir toutes RGR AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- Intracellular
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Réactivité croisée
- Souris, Rat
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Attributs du produit
- The rat alpha 2b adrenergic receptor is a G protein coupled receptor which acts through Gi2 and is responsible for Cellular communication and signal transduction. These receptors are linked to pertussis toxin-sensitive G proteins. Agonist binding leads to inhibition of adenylyl cyclase, inhibition of Ca(2+) channels and activation of K(+) channels. Recently, three distinct subtypes of alpha(2)-AR were described, alpha(2A)-AR, alpha(2B)-AR and alpha(2C)-AR. At present, it is unknown which of these alpha(2)-AR subtype(s) may regulate insulin secretion.
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Purification
- Protein A/G Chromatography
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Immunogène
- Mouse monoclonal antibody raised to a synthetic peptide corresponding to the third intracellular loop of the rat alpha 2b adrenergic receptor.
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Isotype
- IgG1
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Indications d'application
- Antibody detects alpha2B Adrenergic Receptors in Western blots (1-5 μg/mL) and immunohistochemistry. Optimal concentration should be evaluated by serial dilutions.
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Restrictions
- For Research Use only
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Buffer
- Provided as solution in phosphate buffered saline with 0.08 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- RGR (Retinal G Protein Coupled Receptor (RGR))
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Autre désignation
- Adrenergic Receptor
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UniProt
- P19328
Antigène
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