Sphingomyelin Synthase 1 anticorps
Aperçu rapide pour Sphingomyelin Synthase 1 anticorps (ABIN306949)
Antigène
Voir toutes Sphingomyelin Synthase 1 (SGMS1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- Rabbit anti Human Sphingomyelin Synthase 1 (Peptide as antigen)
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Attributs du produit
- A bidirectional lipid cholinephosphotransferases capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and the inverse reaction. Direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors. Directly and specifically recognizes the choline head group on the substrate. Also requires two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. May not function strictly as a SM synthase. Inhibited by bacterial PC-phospholipase C inhibitor D609. Localized to Golgi apparatus, Golgi membrane, multi-pass membrane protein. Possibly present on Brain, heart, kidney, liver, muscle and stomach.
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Purification
- High Salt Precipitation
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Indications d'application
- Antibody can be used for Western blotting (5-10 μg/mL). Optimal concentration should be evaluated by serial dilutions.
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Restrictions
- For Research Use only
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Concentration
- 1 mg/ml
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Stock
- -20 °C
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Stockage commentaire
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- Sphingomyelin Synthase 1 (SGMS1)
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Autre désignation
- Sphingomyelin Synthase 1
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Sujet
- Phosphatidylcholine:ceramide cholinephosphotransferase 1 Transmembrane protein 23, Sphingomyelin synthase 1, Mob protein
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UniProt
- Q86VZ5
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Pathways
- Cellular Response to Molecule of Bacterial Origin
Antigène
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