TIMP1 anticorps

N° du produit ABIN307121

L’anticorps anti-TIMP1 Monoclonal Souris est utilisé pour la détection de TIMP1 dans des échantillons de Humain et Primate. Il a été validé pour WB, IHC et ELISA.

Aperçu rapide pour TIMP1 anticorps (ABIN307121)

Antigène: TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

Reactivité: Humain, Primate

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TIMP1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 2A5

Détail du produit anti-TIMP1 anticorps

Fonction: Mouse anti Human Tissue Inhibitor of Matrix Metalloproteinase 1 (TIMP-1)

Réactivité croisée: Humain, Macaque

Attributs du produit: TIMP-1, TIMP-2, TIMP-3 and TIMP-4 (for tissue inhibitor of metalloproteinases-1, -2, -3 and -4) complex with metalloproteinases such as collagenases, gelatinases and stromelysins, resulting in irreversible inactivation of the metalloproteinase. TIMP-1 was found to be identical to EPA (erythroidpotentiation activity). Parathyroid hormone has been shown to be a regulator of TIMP-2 in osteoblastic cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes. TIMP-4 is most highly expressed in heart and low levels of TIMP-4 are expressed in liver, brain, lung, thymus and spleen.

Purification: Protein A/G Chromatography

Immunogène: Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with a synthetic peptide derived from the human TIMP-1 protein and mouse myeloma Ag8563 cells. Sequence common in monkey

Isotype: IgG1

Information d'application

Indications d'application: Antibody can be used for Western blotting (1-2 μg/mL) and immunohistochemistry on formalin-fixed, paraffin-embedded tissues (1-5 μg/mL). Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: phosphate buffered saline with 0.08 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Détails sur TIMP1

Antigène: TIMP1 (TIMP Metallopeptidase Inhibitor 1 (TIMP1))

Autre désignation: Tissue Inhibitor of Matrix Metalloproteinase 1 (TIMP-1)

Sujet: TIMP-1, CLG1, EPA, HCI

UniProt: P01033, Q95KL9