CCT8L2 anticorps (C-Term)
Aperçu rapide pour CCT8L2 anticorps (C-Term) (ABIN307125)
Antigène
Voir toutes CCT8L2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- C-Term
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Fonction
- Mouse anti Human T-Complex Protein 1, subunit
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Réactivité croisée
- Grenouille, Humain, Souris, Rat
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Attributs du produit
- The protein TCP-1 (t-complex polypeptide 1) is a subunit of the hetero-oligomeric complex CCT (chaperonin containing TCP-1) present in the eukaryotic cytosol. The CCT of eukaryotic cytosol is composed of eight different subunit species that are proposed to have independent functions in folding its in vivo substrates, the Actins and Tubulins. TCP-1 was first identified in the mouse as relevant for tail-less and embryonic lethal phenotypes. Sequences homologous to TCP-1 have been isolated in several other species, and the yeast TCP-1 has been shown to encode a molecular chaperone for Actin and Tubulin. TCP-1 found in mammalian cells and yeast plays an important role in the folding of cytosolic proteins.
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Purification
- Protein A/G Chromatography
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Immunogène
- Hybridoma produced by the fusion of splenocytes from BALB/c mice immunized with a synthetic peptide derived from the C-terminal of the TCP-1 protein and mouse myeloma Ag8563 cells. Sequence common in human, frog, mouse, rat
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Isotype
- IgG2a
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Indications d'application
- Antibody can be used for Western blotting (1-2 μg/mL) and immunohistochemistry on formlin-fixed, paraffin-embedded tissue sections (1-5 μg/mL). Optimal concentration should be evaluated by serial dilutions.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- phosphate buffered saline with 0.08 % sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles
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- CCT8L2 (Chaperonin Containing TCP1, Subunit 8 (Theta)-Like 2 (CCT8L2))
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Autre désignation
- T-Complex Protein 1
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Sujet
- TCP-1b, Chaperonin containing TCP1, subunit 2 (beta), CCT-beta, CCTB
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UniProt
- P47207
Antigène
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