LASS1 anticorps (C-Term)

N° du produit ABIN307129

Cet anticorps Lapin Polyclonal détecte spécifiquement LASS1 dans WB. Il présente une réactivité envers Humain.

Aperçu rapide pour LASS1 anticorps (C-Term) (ABIN307129)

Antigène: LASS1 (CERS1) (Ceramide Synthase 1 (CERS1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp LASS1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-LASS1 anticorps

Épitope: C-Term

Réactivité croisée: Humain

Attributs du produit: LAG1 longevity assurance homolog 1, UOG-1 protein, LAG1, LASS1,LAG1 is a longevity gene, the first such gene to be identified. Originally cloned from the yeast Saccharomyces cerevisiae. A close homolog of this gene, LAC1, has been found in the yeast genome. The human homolog of LAG1 has functions in human aging. LAG1 may be involved in neurodegenerative diseases and human aging. Lass1 may be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked stearoyl- (C18) ceramide) in a fumonisin B1-independent manner. Located in the endoplasmic reticulum membrane, LAss1 is a multi-pass membrane protein.

Purification: Ammonium Sulfate Precipitation

Immunogène: Synthetic peptide derived from the C-terminal human Lass1 protein.

Isotype: IgG

Information d'application

Indications d'application: Antibody can be used for Western blotting (1-5 μg/mL starting dilution). Other uses not yet tested. Only reacts with human Lass1 protein. Does not cross react with other species. Optimal concentration should be evaluated by serial dilutions.

Restrictions: For Research Use only

Stockage

Buffer: Provided as solution in phosphate buffered saline with 0.08 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Détails sur LASS1

Antigène: LASS1 (CERS1) (Ceramide Synthase 1 (CERS1))

Autre désignation: Lass1 (non-GDF1)

UniProt: P27544