CD81 anticorps (PE)

N° du produit ABIN307700

Détail du produit anti-CD81 anticorps (PE)

Antigène: CD81

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD81 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Specificité: Reacts with the extracellular loops of murine CD81 (TAPA-1) molecule. As a member of the tetraspanin superfamily of cell-surface proteins, CD81 has been linked to the control of cell proliferation, adhesion and motility. CD81 is expressed in higher levels on resting murine B cells than on resting T cells and is functionally active on B cells as it induces homotypic adhesion of B lymphocytes. Unlike human CD81, which is expressed equally on all thymocytes, murine CD81 is upregulated on CD4+CD8+ thymocytes, then down-regulated again on mature single-positive thymocytes. Murine dendritic cells, splenic macrophages and NK cells all express very high levels of CD81. CD81 has also been involved in the induction of IL-4 secretion from T cells during Th2 immune responses. It has been reported that CD81 expression can also be induced in mature T cells upon activation. This anti-CD81 mAb has been shown to decrease the proliferation of LPS stimulated CD81+/+ B cells to levels similar to that of CD81-/- B cells

Purification: Purified

Immunogène:

Type of Immunogen: Native protein

Clone: Eat2

Isotype: IgG1

Information d'application

Indications d'application: Approved: Flo

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Commentaires:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.02 % sodium azide, EIA grade BSA.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Détails sur CD81

Antigène: CD81

Autre désignation: CD81 (CD81 Produits)

Synonymes: anticorps Tapa-1, anticorps Tapa1, anticorps Tspan28, anticorps CVID6, anticorps S5.7, anticorps TAPA1, anticorps TSPAN28, anticorps CD81 molecule, anticorps CD81 molecule b, anticorps CD81 antigen, anticorps Cd81 molecule, anticorps CD81, anticorps cd81b, anticorps Cd81

Sujet: Name/Gene ID: CD81
Family: Tetraspan

Synonyms: CD81, CD81 antigen, CD81 Molecule, CVID6, S5.7, TAPA1, TAPA-1, Tetraspanin-28, TSPAN28, Tspan-28

ID gène: 975

UniProt: P60033

Pathways: Inositol Metabolic Process, Hepatitis C