TIM3 anticorps (FITC)

N° du produit ABIN308140

Cet anticorps Rat Monoclonal détecte spécifiquement TIM3 dans FACS et IHC. Il présente une réactivité envers Souris.

Aperçu rapide pour TIM3 anticorps (FITC) (ABIN308140)

Antigène: TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp TIM3 est conjugé à/à la FITC

Application: Flow Cytometry (FACS), Immunohistochemistry (IHC)

Clone: 25F-1D6

Détail du produit anti-TIM3 anticorps (FITC)

Specificité: Anti-mouse Tim-3 (T cell immunoglobulin domain, mucin domain 3) monoclonal antibody reacts with mouse Tim-3. This 281 amino acid type 1 transmembrane protein contains an immunoglobulin and mucin-like domain in its extra-cellular portion and a tyrosine phosphorylation motif in its cytoplasmic portion. Tim-3 is a member of the immunoglobulin super-family and is expressed on Th1 lymphocytes and CD11b+ macrophages. Tim-3 is a T helper type 1 (TH1)-specific molecule that regulates TH1 mediated auto and alloimmune responses and the induction of peripheral immunological tolerance. This antibody has been reported to work in Flow Cytometry and Immunohistochemistry. This FITC conjugated format is especially useful for direct flow cytometry.

Purification: Purified

Immunogène: Murine T cell clone AE7 cells.

Isotype: IgG2a kappa

Information d'application

Indications d'application: Approved: Flo (1 μg/10 x10⁶), IHC

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Commentaires:

Target Species of Antibody: Mouse

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.02 % sodium azide, EIA grade BSA.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze-thaw cycles and prolonged exposure to light. Store undiluted.

Stock: 4 °C,-20 °C

Stockage commentaire: Short term: store at 4°C. Long term: aliquot and store -20°C. Avoid freeze-thaw cycles. Protect from light. Store undiluted.

Détails sur TIM3

Antigène: TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))

Autre désignation: HAVCR2 / TIM-3

Classe de substances: Virus

Sujet: Name/Gene ID: HAVCR2

Synonyms: HAVCR2, HAVcr-2, KIM-3, Kidney injury molecule-3, T cell immunoglobulin mucin 3, Tim-3, TIMD3, T-cell membrane protein 3, TIM3, TIMD-3, T cell immunoglobulin mucin-3

ID gène: 84868

UniProt: Q8TDQ0

Pathways: Regulation of Lipid Metabolism by PPARalpha, Cancer Immune Checkpoints