CD24 anticorps

N° du produit ABIN316591

Cet anticorps Souris Monoclonal détecte spécifiquement CD24 dans FACS et IHC (fro). Il présente une réactivité envers Humain.

Aperçu rapide pour CD24 anticorps (ABIN316591)

Antigène: CD24 (CD24 Molecule (CD24))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD24 est non-conjugé

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: SN3

Détail du produit anti-CD24 anticorps

Attributs du produit: Synonyms: X62 heat stable antigen, HSA, Signal transducer CD24, Small cell lung carcinoma cluster 4antigen

Purification: Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant

niveau d'endotoxine: Low Endotoxin

Immunogène: Glycoproteins purified from human NALM-1 cell line

Isotype: IgG1

Information d'application

Indications d'application: Immunohistochemistry on frozen sections. Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline pH 7.4

Stock: -20 °C

Stockage commentaire: Store the antibody at -20 °C. Avoid repeated freezing and thawing.
Shelf life: one year from despatch. Caution: (A full Health and Safety assessment is available upon request)

Date de péremption: 12 months

Détails sur CD24

Antigène: CD24 (CD24 Molecule (CD24))

Autre désignation: CD24

Sujet: CD24 (also known as heat stable antigen) is a phosphatidylinositol linked cell surface glycoprotein with a polypeptide core of 30 amino acids and high carbohydrate content. The apparent molecular mass of the two forms of CD24 purified from a mouse lymphoma cell line appear to be in the range of 40-60 and 23-30 kDa. CD24 is expressed at all stages of B cell development and on most thymocytes. The absence of expression from mature T cells is closely associated with their maturation from CD4+ CD8+ CD24+ thymocytes to either CD4+ CD8- CD24- or CD4- CD8+ CD24- T cells. CD24 is also present on mouse granulocytes, monocytes, Langerhans cells and erythrocytes. Its ligand is P selectin (CD62P). CD24 may play a role in regulation of B cell proliferation and differentiation, and it has been proposed that heat stable antigen promotes homotypic adhesion between B lymphocytes. CD24 is also a positive marker of pancreatic cancer.Synonyms: HSA, Signal transducer CD24, Small cell lung carcinoma cluster 4 antigen, X62 heat stable antigen

UniProt: P25063

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation